Browsing Journal Articles by Author "Van Brummelen, AC"

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In vitro anti-plasmodial activity of Dicoma anomala subsp. gerrardii (Asteraceae): identification of its main active constituent, structure-activity relationship studies and gene expression profiling

Author: Becker, JVW ; Van der Merwe, MM ; Van Brummelen, AC ; Pillay, P ; Crampton, BG ; Mmutlane, EM ; Parkinson, C ; Van Heerden, FR ; Crouch, NR ; Smith, PJ ; Mancama, Dalubuhle T ; Maharaj, VJ Date: Oct 2011 Anti-malarial drug resistance threatens to undermine efforts to eliminate this deadly disease. The resulting omnipresent requirement for drugs with novel modes of action prompted a national consortium initiative to discover new anti-plasmodial ... Read more
Plasmodium falciparum spermidine synthase inhibition results in unique perturbation-specific effects observed on transcript, protein and metabolite levels

Author: Becker, JVW ; Mtwisha, L ; Crampton, BG ; Stoychev, Stoyan H ; Van Brummelen, AC ; Reeksting, S ; Louw, AI ; Birkholtz, LM ; Mancama, Dalubuhle T Date: Jan 2010 This study details the malaria parasite's response to PfSpdSyn inhibition on the transcriptomic, proteomic and metabolic levels. The results corroborate and significantly expand previous functional genomics studies relating to polyamine ... Read more

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Browsing Journal Articles by Author "Van Brummelen, AC"

Browsing Journal Articles by Author "Van Brummelen, AC"

Browse

All of ResearchSpace

This Collection

Quick Links

Legislation and compliance

General Enquiries

Social Connect