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Browsing by Subject "Antimalarial drugs"

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Heterologous expression of plasmodial proteins for structural studies and functional annotation

Author: Birkholtz, LM ; Blatch, G ; Coetzer, TL ; Hoppe, HC ; Human, E ; Morris, EJ ; Ngcete, Z ; Oldfield, LC ; Roth, Robyn L ; Shonhai, A ; Stephens, L ; Louw, AI Date: 2008 Malaria remains the world's most devastating tropical infectious disease with as many as 40% of the world population living in risk areas. The widespread resistance of plasmodium parasites to the cost-effective chloroquine and antifolates has ... Read more
Investigating South African plants as a source of new antimalarial drugs

Author: Pillay, P ; Maharaj, VJ ; Smith, PJ Date: Oct 2008 Based on the historical success of natural products as antimalarial drugs and the urgent need for new antimalarials, a number of South African medicinal plants have been evaluated for their antimalarial properties. This paper reviews the major ... Read more
Pyrimidines in antimalarial drug design

Author: Moleele, SS ; Gravestock, D ; Rousseau, AL ; Van Zyl, RL Date: Sep 2008 Malaria causes the death of 2-3 million people annually, most of these children under 5 years of age. Approximately 300 million cases of acute malaria are reported each year, 90% of these in Africa. Until recently, folate metabolism has been ... Read more

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Browsing by Subject "Antimalarial drugs"

Browsing by Subject "Antimalarial drugs"

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