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Please use this identifier to cite or link to this item: http://hdl.handle.net/10204/3367

Title: Investigating South African plants as a source of new antimalarial drugs
Authors: Pillay, P
Maharaj, VJ
Smith, PJ
Keywords: Medicinal plants
Antimalarial drugs
Natural drug products
South Africa
Malaria
Ethnopharmacology
Antiplasmodial screening,
Bioassay-guided fractionation
Sesquiterpene lactones
Cytotoxicity
Issue Date: Oct-2008
Publisher: Elsevier
Citation: Pillay, P, Maharaj, VJ and Smith, PJ. 2008. Investigating South African plants as a source of new antimalarial drugs. Journal of Ethnopharmacology, Vol. 119(3), pp 1-27
Abstract: Based on the historical success of natural products as antimalarial drugs and the urgent need for new antimalarials, a number of South African medicinal plants have been evaluated for their antimalarial properties. This paper reviews the major studies conducted and their findings. Overall three ethnobotanical screening programmes have been conducted on South African plants and there have been three studies adopting a more direct approach where plants within a particular genus were screened for antiplasmodial activity. The paper also summarizes antimalarial plants, which were studied individually, as well as the bioactive molecules identified from selected active plant extracts
Description: Author Posting. Copyright Elsevier, 2008. This is the author's version of the work. It is posted here by permission of Elsevier for personal use, not for redistribution
URI: http://hdl.handle.net/10204/3367
ISSN: 0378-8741
Appears in Collections:General science, engineering & technology
Discovery chemistry

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