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Exploration of the biomacromolecular interactions of an interpenetrating proteo-saccharide hydrogel network at the mucosal interface

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dc.contributor.author Mashingaidze, F
dc.contributor.author Choonara, YE
dc.contributor.author Kumar, P
dc.contributor.author Du Toit, LC
dc.contributor.author Maharaj, V
dc.contributor.author Buchmann, E
dc.contributor.author Ndesendo, VMK
dc.contributor.author Pillay, V
dc.date.accessioned 2013-09-30T08:05:01Z
dc.date.available 2013-09-30T08:05:01Z
dc.date.issued 2013-09
dc.identifier.citation Mashingaidze, F, Choonara, Y.E, Kumar, P, du Toit L.C, Maharaj, V, Buchmann, E, Ndesendo, V.M.K and Pillay, V. 2013. Exploration of the biomacromolecular interactions of an interpenetrating proteo-saccharide hydrogel network at the mucosal interface. Journal of Biomedical Materials Research Part A, pp 1-14 en_US
dc.identifier.issn 1549-3296
dc.identifier.uri http://onlinelibrary.wiley.com/doi/10.1002/jbm.a.34664/pdf
dc.identifier.uri http://hdl.handle.net/10204/6966
dc.description Copyright: 2013 Wiley-Blackwell This is an ABSTRACT ONLY. The definitive version is published in Journal of Biomedical Materials Research Part A, pp 1-14 en_US
dc.description.abstract The relationship between mucin (MUC) and pectin (PEC) was explored in an attempt to understand the biomacro-molecular interactions that occur at mucosal surfaces when mucus membranes are exposed to PEC-based materials. These interactions were explored through techniques, such as attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy, SEM imagery of lyophilized MUC–PEC blends, thermodynamic analysis, rheology investigations, and in silico static lattice atomistic simulations using a molecular mechanics energy relationships (MMER) approach. en_US
dc.language.iso en en_US
dc.publisher Wiley-Blackwell en_US
dc.relation.ispartofseries Worklist;11530
dc.subject Pectin en_US
dc.subject Mucin en_US
dc.subject Macromolecular interaction en_US
dc.subject Synergistic enhancement in rheology en_US
dc.subject Molecular mechanics en_US
dc.subject Energy relationships en_US
dc.title Exploration of the biomacromolecular interactions of an interpenetrating proteo-saccharide hydrogel network at the mucosal interface en_US
dc.type Article en_US
dc.identifier.apacitation Mashingaidze, F., Choonara, Y., Kumar, P., Du Toit, L., Maharaj, V., Buchmann, E., ... Pillay, V. (2013). Exploration of the biomacromolecular interactions of an interpenetrating proteo-saccharide hydrogel network at the mucosal interface. http://hdl.handle.net/10204/6966 en_ZA
dc.identifier.chicagocitation Mashingaidze, F, YE Choonara, P Kumar, LC Du Toit, V Maharaj, E Buchmann, VMK Ndesendo, and V Pillay "Exploration of the biomacromolecular interactions of an interpenetrating proteo-saccharide hydrogel network at the mucosal interface." (2013) http://hdl.handle.net/10204/6966 en_ZA
dc.identifier.vancouvercitation Mashingaidze F, Choonara Y, Kumar P, Du Toit L, Maharaj V, Buchmann E, et al. Exploration of the biomacromolecular interactions of an interpenetrating proteo-saccharide hydrogel network at the mucosal interface. 2013; http://hdl.handle.net/10204/6966. en_ZA
dc.identifier.ris TY - Article AU - Mashingaidze, F AU - Choonara, YE AU - Kumar, P AU - Du Toit, LC AU - Maharaj, V AU - Buchmann, E AU - Ndesendo, VMK AU - Pillay, V AB - The relationship between mucin (MUC) and pectin (PEC) was explored in an attempt to understand the biomacro-molecular interactions that occur at mucosal surfaces when mucus membranes are exposed to PEC-based materials. These interactions were explored through techniques, such as attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy, SEM imagery of lyophilized MUC–PEC blends, thermodynamic analysis, rheology investigations, and in silico static lattice atomistic simulations using a molecular mechanics energy relationships (MMER) approach. DA - 2013-09 DB - ResearchSpace DP - CSIR KW - Pectin KW - Mucin KW - Macromolecular interaction KW - Synergistic enhancement in rheology KW - Molecular mechanics KW - Energy relationships LK - https://researchspace.csir.co.za PY - 2013 SM - 1549-3296 T1 - Exploration of the biomacromolecular interactions of an interpenetrating proteo-saccharide hydrogel network at the mucosal interface TI - Exploration of the biomacromolecular interactions of an interpenetrating proteo-saccharide hydrogel network at the mucosal interface UR - http://hdl.handle.net/10204/6966 ER - en_ZA


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