The relationship between mucin (MUC) and pectin (PEC) was explored in an attempt to understand the biomacro-molecular interactions that occur at mucosal surfaces when mucus membranes are exposed to PEC-based materials. These interactions were explored through techniques, such as attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy, SEM imagery of lyophilized MUC–PEC blends, thermodynamic analysis, rheology investigations, and in silico static lattice atomistic simulations using a molecular mechanics energy relationships (MMER) approach.
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Copyright: 2013 Wiley-Blackwell This is an ABSTRACT ONLY. The definitive version is published in Journal of Biomedical Materials Research Part A, pp 1-14