dc.contributor.author |
Karsten, AE
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|
dc.contributor.author |
Smit, Jacoba E
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|
dc.date.accessioned |
2012-03-22T14:44:10Z |
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dc.date.available |
2012-03-22T14:44:10Z |
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dc.date.issued |
2012-03 |
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dc.identifier.citation |
Karsten, AE and Smit, JE. 2012. Modelling and verification of melanin concentration on human skin type. Photochemistry and Photobiology, vol. 88(2), pp 469-474 |
en_US |
dc.identifier.issn |
0031-8655 |
|
dc.identifier.uri |
http://onlinelibrary.wiley.com/doi/10.1111/j.1751-1097.2011.01044.x/pdf
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dc.identifier.uri |
http://hdl.handle.net/10204/5666
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dc.description |
Copyright: 2011 The American Society of Photobiology. This is the pre-print version of the work. The definitive version is published in Photochemistry and Photobiology, vol. 88(2), pp 469-474 |
en_US |
dc.description.abstract |
Lasers are used in the minimalistic or noninvasive diagnosis and treatment of skin disorders. Less laser light reaches the deeper skin layers in dark skin types, due to its higher epidermal melanin concentration compared with lighter skin. Laser–tissue interaction modeling software can correct for this by adapting the dose applied to the skin. This necessitates an easy and reliable method to determine the skin’s type. Noninvasive measurement of the skin’s melanin content is the best method. However, access to samples of all skin types is often limited and skin-like phantoms are used instead. This study’s objective is to compare experimentally measured absorption features of liquid skin-like phantoms representing Skin Types I–VI with a realistic skin computational model component of ASAP®. Sample UV–VIS transmittance spectra were measured from 370 to 900 nm and compared with simulated results from ASAP® using the same optical parameters. Results indicated nonmonotonic absorption features towards shorter wavelengths, which may allow for more accurate ways of determining melanin concentration and expected absorption through the epidermal layer. This suggests possible use in representing optical characteristics of real skin. However, a more comprehensive model and phantoms are necessary to account for the effects of sun exposure. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
Wiley |
en_US |
dc.relation.ispartofseries |
Workflow;7606 |
|
dc.subject |
Sun exposure effects |
en_US |
dc.subject |
Skin disorders |
en_US |
dc.subject |
Laser skin treatment |
en_US |
dc.subject |
Melanin concentration 1 |
en_US |
dc.subject |
Laser lights |
en_US |
dc.subject |
Melanin |
en_US |
dc.subject |
Skin type |
en_US |
dc.subject |
Computational modelling |
en_US |
dc.subject |
Skin-like phantoms |
en_US |
dc.subject |
Skin-like phantoms |
en_US |
dc.subject |
Sun exposure |
en_US |
dc.subject |
Melanin concentration |
en_US |
dc.subject |
Absorption spectroscopy |
en_US |
dc.subject |
Skin models |
en_US |
dc.subject |
Liquid skin-like phantoms |
en_US |
dc.subject |
Non-monotonic absorption features |
en_US |
dc.title |
Modelling and verification of melanin concentration on human skin type |
en_US |
dc.type |
Article |
en_US |
dc.identifier.apacitation |
Karsten, A., & Smit, J. E. (2012). Modelling and verification of melanin concentration on human skin type. http://hdl.handle.net/10204/5666 |
en_ZA |
dc.identifier.chicagocitation |
Karsten, AE, and Jacoba E Smit "Modelling and verification of melanin concentration on human skin type." (2012) http://hdl.handle.net/10204/5666 |
en_ZA |
dc.identifier.vancouvercitation |
Karsten A, Smit JE. Modelling and verification of melanin concentration on human skin type. 2012; http://hdl.handle.net/10204/5666. |
en_ZA |
dc.identifier.ris |
TY - Article
AU - Karsten, AE
AU - Smit, Jacoba E
AB - Lasers are used in the minimalistic or noninvasive diagnosis and treatment of skin disorders. Less laser light reaches the deeper skin layers in dark skin types, due to its higher epidermal melanin concentration compared with lighter skin. Laser–tissue interaction modeling software can correct for this by adapting the dose applied to the skin. This necessitates an easy and reliable method to determine the skin’s type. Noninvasive measurement of the skin’s melanin content is the best method. However, access to samples of all skin types is often limited and skin-like phantoms are used instead. This study’s objective is to compare experimentally measured absorption features of liquid skin-like phantoms representing Skin Types I–VI with a realistic skin computational model component of ASAP®. Sample UV–VIS transmittance spectra were measured from 370 to 900 nm and compared with simulated results from ASAP® using the same optical parameters. Results indicated nonmonotonic absorption features towards shorter wavelengths, which may allow for more accurate ways of determining melanin concentration and expected absorption through the epidermal layer. This suggests possible use in representing optical characteristics of real skin. However, a more comprehensive model and phantoms are necessary to account for the effects of sun exposure.
DA - 2012-03
DB - ResearchSpace
DP - CSIR
KW - Sun exposure effects
KW - Skin disorders
KW - Laser skin treatment
KW - Melanin concentration 1
KW - Laser lights
KW - Melanin
KW - Skin type
KW - Computational modelling
KW - Skin-like phantoms
KW - Skin-like phantoms
KW - Sun exposure
KW - Melanin concentration
KW - Absorption spectroscopy
KW - Skin models
KW - Liquid skin-like phantoms
KW - Non-monotonic absorption features
LK - https://researchspace.csir.co.za
PY - 2012
SM - 0031-8655
T1 - Modelling and verification of melanin concentration on human skin type
TI - Modelling and verification of melanin concentration on human skin type
UR - http://hdl.handle.net/10204/5666
ER -
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en_ZA |