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Please use this identifier to cite or link to this item: http://hdl.handle.net/10204/5666

Title: Modelling and verification of melanin concentration on human skin type
Authors: Karsten, AE
Smit, JE
Keywords: Sun exposure effects
Skin disorders
Laser skin treatment
Melanin concentration 1
Laser lights
Skin type
Computational modelling
Skin-like phantoms
Skin-like phantoms
Sun exposure
Melanin concentration
Absorption spectroscopy
Skin models
Liquid skin-like phantoms
Non-monotonic absorption features
Issue Date: Mar-2012
Publisher: Wiley
Citation: Karsten, AE and Smit, JE. 2012. Modelling and verification of melanin concentration on human skin type. Photochemistry and Photobiology, vol. 88(2), pp 469-474
Series/Report no.: Workflow;7606
Abstract: Lasers are used in the minimalistic or noninvasive diagnosis and treatment of skin disorders. Less laser light reaches the deeper skin layers in dark skin types, due to its higher epidermal melanin concentration compared with lighter skin. Laser–tissue interaction modeling software can correct for this by adapting the dose applied to the skin. This necessitates an easy and reliable method to determine the skin’s type. Noninvasive measurement of the skin’s melanin content is the best method. However, access to samples of all skin types is often limited and skin-like phantoms are used instead. This study’s objective is to compare experimentally measured absorption features of liquid skin-like phantoms representing Skin Types I–VI with a realistic skin computational model component of ASAP®. Sample UV–VIS transmittance spectra were measured from 370 to 900 nm and compared with simulated results from ASAP® using the same optical parameters. Results indicated nonmonotonic absorption features towards shorter wavelengths, which may allow for more accurate ways of determining melanin concentration and expected absorption through the epidermal layer. This suggests possible use in representing optical characteristics of real skin. However, a more comprehensive model and phantoms are necessary to account for the effects of sun exposure.
Description: Copyright: 2011 The American Society of Photobiology. This is the pre-print version of the work. The definitive version is published in Photochemistry and Photobiology, vol. 88(2), pp 469-474
URI: http://onlinelibrary.wiley.com/doi/10.1111/j.1751-1097.2011.01044.x/pdf
ISSN: 0031-8655
Appears in Collections:Laser physics and technology
Information security
Advanced mathematical modelling and simulation
General science, engineering & technology
General research interest

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