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Structure elucidation and stereoselective total synthesis of pavettamine, the causal agent of gousiekte

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dc.contributor.author Bode, ML
dc.contributor.author Gates, PJ
dc.contributor.author Gebretnsae, SY
dc.contributor.author Vleggaar, R
dc.date.accessioned 2010-11-08T14:50:55Z
dc.date.available 2010-11-08T14:50:55Z
dc.date.issued 2010-03
dc.identifier.citation Bode, ML, Gates, PJ, Gebretnsae, SY and Vleggaar, R. 2010. Structure elucidation and stereoselective total synthesis of pavettamine, the causal agent of gousiekte. Tetrahedron, Vol. 66(11), pp 2026-2036 en
dc.identifier.issn 0040-4020
dc.identifier.uri http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6THR-4Y65S94-6-M&_cdi=5289&_user=958262&_pii=S004040201000075X&_orig=search&_coverDate=03/13/2010&_sk=999339988&view=c&wchp=dGLbVtb-zSkWb&_valck=1&md5=e8940ee4d4fd8a01a24f0d3c9ece1c87&ie=/sdarticle.pdf
dc.identifier.uri http://hdl.handle.net/10204/4546
dc.description Copyright: 2010 Elsevier. This is the authors pre print version of the work. The definitive version is published in Tetrahedron, Vol. 66(11), pp 2026-2036 en
dc.description.abstract The structure elucidation of a novel natural product pavettamine (1), the causal agent of the plant toxicosis gousiekte, is reported. The structure was defined by analysis of NMR and MS data and the relative configuration followed from the 13C NMR data of the acetonide derivative. The absolute stereochemistry was established by total synthesis from (2S)-malic acid using chiral sulfoxide methodology as (2S,4R,8R,10S)-1,11-diamino-6-aza-undecane-2,4,8,10-tetraol. en
dc.language.iso en en
dc.relation.ispartofseries Journal Article en
dc.subject Gousiekte en
dc.subject Pavettamine en
dc.subject Structure elucidation en
dc.subject Polyamine synthesis en
dc.title Structure elucidation and stereoselective total synthesis of pavettamine, the causal agent of gousiekte en
dc.type Article en
dc.identifier.apacitation Bode, M., Gates, P., Gebretnsae, S., & Vleggaar, R. (2010). Structure elucidation and stereoselective total synthesis of pavettamine, the causal agent of gousiekte. http://hdl.handle.net/10204/4546 en_ZA
dc.identifier.chicagocitation Bode, ML, PJ Gates, SY Gebretnsae, and R Vleggaar "Structure elucidation and stereoselective total synthesis of pavettamine, the causal agent of gousiekte." (2010) http://hdl.handle.net/10204/4546 en_ZA
dc.identifier.vancouvercitation Bode M, Gates P, Gebretnsae S, Vleggaar R. Structure elucidation and stereoselective total synthesis of pavettamine, the causal agent of gousiekte. 2010; http://hdl.handle.net/10204/4546. en_ZA
dc.identifier.ris TY - Article AU - Bode, ML AU - Gates, PJ AU - Gebretnsae, SY AU - Vleggaar, R AB - The structure elucidation of a novel natural product pavettamine (1), the causal agent of the plant toxicosis gousiekte, is reported. The structure was defined by analysis of NMR and MS data and the relative configuration followed from the 13C NMR data of the acetonide derivative. The absolute stereochemistry was established by total synthesis from (2S)-malic acid using chiral sulfoxide methodology as (2S,4R,8R,10S)-1,11-diamino-6-aza-undecane-2,4,8,10-tetraol. DA - 2010-03 DB - ResearchSpace DP - CSIR KW - Gousiekte KW - Pavettamine KW - Structure elucidation KW - Polyamine synthesis LK - https://researchspace.csir.co.za PY - 2010 SM - 0040-4020 T1 - Structure elucidation and stereoselective total synthesis of pavettamine, the causal agent of gousiekte TI - Structure elucidation and stereoselective total synthesis of pavettamine, the causal agent of gousiekte UR - http://hdl.handle.net/10204/4546 ER - en_ZA


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