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Investigating South African plants as a source of new antimalarial drugs

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dc.contributor.author Pillay, P
dc.contributor.author Maharaj, VJ
dc.contributor.author Smith, PJ
dc.date.accessioned 2009-05-11T07:43:48Z
dc.date.available 2009-05-11T07:43:48Z
dc.date.issued 2008-10
dc.identifier.citation Pillay, P, Maharaj, VJ and Smith, PJ. 2008. Investigating South African plants as a source of new antimalarial drugs. Journal of Ethnopharmacology, Vol. 119(3), pp 1-27 en
dc.identifier.issn 0378-8741
dc.identifier.uri http://hdl.handle.net/10204/3367
dc.description Author Posting. Copyright Elsevier, 2008. This is the author's version of the work. It is posted here by permission of Elsevier for personal use, not for redistribution en
dc.description.abstract Based on the historical success of natural products as antimalarial drugs and the urgent need for new antimalarials, a number of South African medicinal plants have been evaluated for their antimalarial properties. This paper reviews the major studies conducted and their findings. Overall three ethnobotanical screening programmes have been conducted on South African plants and there have been three studies adopting a more direct approach where plants within a particular genus were screened for antiplasmodial activity. The paper also summarizes antimalarial plants, which were studied individually, as well as the bioactive molecules identified from selected active plant extracts en
dc.language.iso en en
dc.publisher Elsevier en
dc.subject Medicinal plants en
dc.subject Antimalarial drugs en
dc.subject Natural drug products en
dc.subject South Africa en
dc.subject Malaria en
dc.subject Ethnopharmacology en
dc.subject Antiplasmodial screening, en
dc.subject Bioassay-guided fractionation en
dc.subject Sesquiterpene lactones en
dc.subject Cytotoxicity en
dc.title Investigating South African plants as a source of new antimalarial drugs en
dc.type Article en
dc.identifier.apacitation Pillay, P., Maharaj, V., & Smith, P. (2008). Investigating South African plants as a source of new antimalarial drugs. http://hdl.handle.net/10204/3367 en_ZA
dc.identifier.chicagocitation Pillay, P, VJ Maharaj, and PJ Smith "Investigating South African plants as a source of new antimalarial drugs." (2008) http://hdl.handle.net/10204/3367 en_ZA
dc.identifier.vancouvercitation Pillay P, Maharaj V, Smith P. Investigating South African plants as a source of new antimalarial drugs. 2008; http://hdl.handle.net/10204/3367. en_ZA
dc.identifier.ris TY - Article AU - Pillay, P AU - Maharaj, VJ AU - Smith, PJ AB - Based on the historical success of natural products as antimalarial drugs and the urgent need for new antimalarials, a number of South African medicinal plants have been evaluated for their antimalarial properties. This paper reviews the major studies conducted and their findings. Overall three ethnobotanical screening programmes have been conducted on South African plants and there have been three studies adopting a more direct approach where plants within a particular genus were screened for antiplasmodial activity. The paper also summarizes antimalarial plants, which were studied individually, as well as the bioactive molecules identified from selected active plant extracts DA - 2008-10 DB - ResearchSpace DP - CSIR KW - Medicinal plants KW - Antimalarial drugs KW - Natural drug products KW - South Africa KW - Malaria KW - Ethnopharmacology KW - Antiplasmodial screening, KW - Bioassay-guided fractionation KW - Sesquiterpene lactones KW - Cytotoxicity LK - https://researchspace.csir.co.za PY - 2008 SM - 0378-8741 T1 - Investigating South African plants as a source of new antimalarial drugs TI - Investigating South African plants as a source of new antimalarial drugs UR - http://hdl.handle.net/10204/3367 ER - en_ZA


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