Author:Pillay, P; Maharaj, VJ; Clarkson, C; Chibale, KDate:Jan 2007Malaria is the leading cause of death and disease worldwide. The evolution and spread of drug-resistant forms of the causative agent Plasmodium falciparum and the limited number of chemotherapeutic agents available to treat and control the ...Read more
Author:Pillay, P; Maharaj, V; Crouch, N; Smith, P; Lategan, C; Vleggaar, RDate:Feb 2006With the emergence and spread of drug- resistant parasites, there is a need for new chemically diverse, effective antimalarial drugs. A national multidisciplinary consortium was established to validate scientifically South African medicinal ...Read more
Author:Genthe, Bettina; Ndlela, Luyanda L; Madlala, TebogoDate:Dec 2020According to the Centre for Disease Dynamics Economics and Policy, South Africa represents a paradox of antibiotic management similar to other developing countries, with both overuse and underuse (resulting from lack of access) of antibiotics. ...Read more
Author:Adewusi, EA; Fouché, Gerda; Steenkamp, VDate:Oct 2012Traditional healers use Boophane disticha to treat several neurodegenerative diseases. Further studies need to be carried out to justify its use in traditional medicine.Read more
Author:Kamatou, GGP; Viljoen, AM; Steenkamp, PDate:Mar 2010The antioxidant and antiinflammatory activities of the methanol:chloroform (1:1) extracts of 16 Salvia species indigenous to South Africa were evaluated. Antioxidant activity was measured using the 2,20- azino-bis (3-ethylbenzothiazoline-6-sulfonic ...Read more
Author:Kadhila, NP; Sekhoacha, M; Tselanyane, Malefa L; Chinsembu, KCDate:Dec 2018This paper looked at basidiomycetes and their antiplasmodial activities from different studies. The purpose of this short review is to encourage more research on fungi in order to address major and complicated infectious diseases like malaria, ...Read more
Author:Pillay, P; Vleggaar, R; Maharaj, VJ; Smith, PJ; Lategan, CA; Chouteau, F; Chibale, KDate:Feb 2007The dichloromethane extract of the leaves of Vernonia staehelinoides Harv. (Asteraceae) showed in vitro activity (IC50 ~3 µg/ml) against the chloroquine-sensitive (D10) and the chloroquine-resistant (K1) strains of Plasmodium falciparum. ...Read more
Author:George, BPA; Kumar, Neeraj; Abrahamse, H; Ray, Suprakas SDate:Sep 2018Metallic nanoparticles (NPs) especially silver (Ag) NPs have shown immense potential in medical applications due to their distinctive physio-chemical and biological properties. This article reports the conjugation of Ag NPs with Rubus ...Read more
Author:Viljoen, GADate:1972The first apparatus operating on the principle of a change in the buoyant force with progressive settling was constructed along the following lines. A suitable shaped glass cylinder was suspended from one arm of a chemical balance so that it ...Read more
Author:Oberholster, Paul J; Botha, AM; Ashton, PJDate:Apr 2009Data generated during 12 field trips in 2006 were used to investigate possible changes in the biota communities of Lake Tswaing after a borehole was sunk in 1988/1989 near the centre of the crater lake. The Tswaing meteorite crater lake is a ...Read more
Author:Van Heerden, FR; Horak, RM; Maharaj, VJ; Vleggaar, R; Senabe, JV; Gunning, PJDate:Apr 2007Two new pregnane glycosides were isolated by fractionation of the dried stems of Hoodia gordonii. Their structures were determined as 3beta-[beta-D-thevetopyranosyl-(1→4)-beta-D-cymaropyranosyl-(1→4)-beta-D-cymaropyranosyloxy]-12beta-tigloy ...Read more
Author:Raab, GADate:1973The effects of mechanisation in coal mining were investigated by the NCB Scientific Department and some data were published in "second Symposium on Coal Preparation" 21st to 25th October, 1957, University of Leeds.Read more
Author:Manzi, MSD; Gibson, MAS; Hein, KAA; King, N; Durrheim, RJDate:Sep 2012As expensive as 3D seismic reflection surveys are, their high cost is justified by improved imaging of certain ore horizons in some of the Witwatersrand basin gold mines. The merged historical 3D seismic reflection data acquired for Kloof and ...Read more
Author:Ramkilowan, A; Griffith, DJDate:Sep 2015Ceilometers operating on several optical principles have been extensively applied to vertical visibility and cloud base measurements relating to aviation safety. The latest generation of laser time-of-flight backscatter ceilometers use the ...Read more
Author:Roberts, MBDate:Feb 1978In the chrome dying of wool by the afterchrome process, a saving of time has been achieved during the dyeing phase by commencing the dyeing at a higher temperature than normal and controlling exhaustion by means of a steady reduction in pH.Read more
Author:Broughton, EK; Brent, AC; Haywood, Lorren KDate:Dec 2012The current decision-making processes that are involved in Environmental Impact Assessments in the energy sector of South Africa suffer from, amongst others, the lack of coherence and the integration of the opinions of decision-makers in the ...Read more