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dc.contributor.author Siva Mohan Reddy, G
dc.contributor.author Jayaramudu, J
dc.contributor.author Sadiku, ER
dc.contributor.author Ray, Suprakas S
dc.contributor.author Varaprasad, K
dc.contributor.author Aderibigbe, BA
dc.date.accessioned 2014-09-16T12:20:20Z
dc.date.available 2014-09-16T12:20:20Z
dc.date.issued 2014
dc.identifier.citation Siva Mohan Reddy, G, Jayaramudu, J, Sadiku, E.R, Ray, S.S., Varaprasad, K. and Aderibigbe, B.A. 2014. Application of cross-linked soy protein isolate with resorcinol films for release studies of naturally occurring bioactive agent with antiproliferative activity. Journal of Drug Delivery Science and Technology, vol. 24(1), pp 86- 91 en_US
dc.identifier.issn 1773-2247
dc.identifier.uri http://www.jddst.com/index.php?id_product=1027&controller=product
dc.identifier.uri http://hdl.handle.net/10204/7673
dc.description Copyright: 2014 Academy of Pharmaceutical Science and Technology (APST). This is an ABSTRACT ONLY. The definitive version is published in Journal of Drug Delivery Science and Technology, vol. 24(1), pp 86-91 en_US
dc.description.abstract The potential of soy protein isolate films as a release system for naturally occurring antiproliferative agent was investigated. The soy protein isolates was cross linked with resorcinol and the resorcinol content was varied between 10-30 %. The release study was monitored over a period of 24 h at a pH of 7.4. Different kinetic release models were used to determine the mechanism of release of bioactive agent from the films. The release profiles of the SPI films of selected degree of cross-linking were anomalous (non-Fickian) and case II transport, with n values in the range of 0.97-1.01. The degree of cross-linking provided an effective means of regulating the release rate of the SPI films, and hence potential for use as drug release system. These films were further characterized by Fourier transform spectroscopy (FTIR), spectroscopy, scanning electron microscope (SEM), X-ray diffraction (XRD) and thermogravimetric analysis (TGA) which confirmed the successful incorporation of curcumin onto the films. en_US
dc.language.iso en en_US
dc.publisher Academy of Pharmaceutical Science and Technology (APST) en_US
dc.relation.ispartofseries Workflow;13379
dc.subject Soy protein isolate films en_US
dc.subject Curcumin en_US
dc.subject Drug release en_US
dc.subject Anticancer en_US
dc.subject Antibacterial en_US
dc.title Application of cross-linked soy protein isolate with resorcinol films for release studies of naturally occurring bioactive agent with antiproliferative activity en_US
dc.type Article en_US


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