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dc.contributor.author Mbanjwa, M
dc.contributor.author Chen, H
dc.contributor.author Fourie, L
dc.contributor.author Ngwenya, S
dc.contributor.author Land, K
dc.date.accessioned 2014-08-25T10:15:25Z
dc.date.available 2014-08-25T10:15:25Z
dc.date.issued 2014-06
dc.identifier.citation Mbanjwa, M, Chen, H, Fourie, L, Ngwenya, S and Land, K. 2014. Fabrication of a multiplexed microfluidic system for scaled up production of cross-linked biocatalytic microspheres. In: Proceeding of SPIE 9257, Sensors, MEMS and Electro-Optical Systems, 92570M, 23 June 2014 en_US
dc.identifier.uri http://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=1884907
dc.identifier.uri http://hdl.handle.net/10204/7625
dc.description Proceeding of SPIE 9257, Sensors, MEMS and Electro-Optical Systems, 92570M, 23 June 2014 en_US
dc.description.abstract Multiplexed or parallelised droplet microfluidic systems allow for increased throughput in the production of emulsions and microparticles, while maintaining a small footprint and utilising minimal ancillary equipment. The current paper demonstrates the design and fabrication of a multiplexed microfluidic system for producing biocatalytic microspheres. The microfluidic system consists of an array of 10 parallel microfluidic circuits, for simultaneous operation to demonstrate increased production throughput. The flow distribution was achieved using a principle of reservoirs supplying individual microfluidic circuits. The microfluidic devices were fabricated in poly (dimethylsiloxane) (PDMS) using soft lithography techniques. The consistency of the flow distribution was determined by measuring the size variations of the microspheres produced. The coefficient of variation of the particles was determined to be 9%, an indication of consistent particle formation and good flow distribution between the 10 microfluidic circuits. en_US
dc.language.iso en en_US
dc.publisher SPIE Digital Library en_US
dc.relation.ispartofseries Workflow;12620
dc.subject Biocatalysts en_US
dc.subject Droplets en_US
dc.subject Emulsion en_US
dc.subject Enzymes en_US
dc.subject Monodisperse en_US
dc.subject Microfluidics en_US
dc.subject Microparticles en_US
dc.subject Parallelisation en_US
dc.subject Scaleup en_US
dc.title Fabrication of a multiplexed microfluidic system for scaled up production of cross-linked biocatalytic microspheres en_US
dc.type Presentation en_US


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