Abstract:
An LC-MS screening method was developed to detect the presence of atractyloside (ATR), the toxic principle of a commonly used medicinal plant in South Africa, Callilepis laureola, in biological matrices such as body fluids and human viscera. The method described is robust and can be adjusted to do full or SIR MS scans, therefore ideally suited for either high concentration or trace level analysis of ATR and CATR in various matrices.