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The effect of temperature and methanol–water mixture on pressurized hot water extraction (PHWE) of anti-HIV analogoues from Bidens pilosa

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dc.contributor.author Gbashi, S
dc.contributor.author Njobeh, P
dc.contributor.author Steenkamp, P
dc.contributor.author Tutu, H
dc.contributor.author Madala, N
dc.date.accessioned 2017-05-12T06:48:55Z
dc.date.available 2017-05-12T06:48:55Z
dc.date.issued 2016-06
dc.identifier.citation Gbashi, S., Njobeh, P., Steenkamp, P. Tutu, H. Madala N. The effect of temperature and methanol–water mixture on pressurized hot water extraction (PHWE) of anti-HIV analogoues from Bidens pilosa. Chemistry Central JournaL, Vol.10 (37), pp. DOI 10.1186/s13065-016-0182-z en_US
dc.identifier.issn 1752-153X
dc.identifier.uri http://hdl.handle.net/10204/9008
dc.identifier.uri https://ccj.springeropen.com/articles/10.1186/s13065-016-0182-z
dc.description Copyright: 2016 The Authors. en_US
dc.description.abstract Pressurized hot water extraction (PHWE) technique has recently gain much attention for the extraction of biologically active compounds from plant tissues for analytical purposes, due to the limited use of organic solvents, its cost-effectiveness, ease-of-use and efficiency. An increase in temperature results in higher yields, however, issues with degradation of some metabolites (e.g. tartrate esters) when PHWE is conditioned at elevated temperatures has greatly limited its use. In this study, we considered possibilities of optimizing PHWE of some specific functional metabolites from Bidens pilosa using solvent compositions of 0, 20, 40 and 60 % methanol and a temperature profile of 50, 100 and 150 °C. en_US
dc.language.iso en en_US
dc.publisher BIOMED CENTRAL LTD en_US
dc.relation.ispartofseries Worklist;18043
dc.subject Pressurized hot water extraction en_US
dc.subject Co-solvent en_US
dc.subject Bidens pilosa en_US
dc.subject Dicaffeoylquinic acid en_US
dc.subject Chicoric acid en_US
dc.subject Response surface modeling en_US
dc.title The effect of temperature and methanol–water mixture on pressurized hot water extraction (PHWE) of anti-HIV analogoues from Bidens pilosa en_US
dc.type Article en_US
dc.identifier.apacitation Gbashi, S., Njobeh, P., Steenkamp, P., Tutu, H., & Madala, N. (2016). The effect of temperature and methanol–water mixture on pressurized hot water extraction (PHWE) of anti-HIV analogoues from Bidens pilosa. http://hdl.handle.net/10204/9008 en_ZA
dc.identifier.chicagocitation Gbashi, S, P Njobeh, P Steenkamp, H Tutu, and N Madala "The effect of temperature and methanol–water mixture on pressurized hot water extraction (PHWE) of anti-HIV analogoues from Bidens pilosa." (2016) http://hdl.handle.net/10204/9008 en_ZA
dc.identifier.vancouvercitation Gbashi S, Njobeh P, Steenkamp P, Tutu H, Madala N. The effect of temperature and methanol–water mixture on pressurized hot water extraction (PHWE) of anti-HIV analogoues from Bidens pilosa. 2016; http://hdl.handle.net/10204/9008. en_ZA
dc.identifier.ris TY - Article AU - Gbashi, S AU - Njobeh, P AU - Steenkamp, P AU - Tutu, H AU - Madala, N AB - Pressurized hot water extraction (PHWE) technique has recently gain much attention for the extraction of biologically active compounds from plant tissues for analytical purposes, due to the limited use of organic solvents, its cost-effectiveness, ease-of-use and efficiency. An increase in temperature results in higher yields, however, issues with degradation of some metabolites (e.g. tartrate esters) when PHWE is conditioned at elevated temperatures has greatly limited its use. In this study, we considered possibilities of optimizing PHWE of some specific functional metabolites from Bidens pilosa using solvent compositions of 0, 20, 40 and 60 % methanol and a temperature profile of 50, 100 and 150 °C. DA - 2016-06 DB - ResearchSpace DP - CSIR KW - Pressurized hot water extraction KW - Co-solvent KW - Bidens pilosa KW - Dicaffeoylquinic acid KW - Chicoric acid KW - Response surface modeling LK - https://researchspace.csir.co.za PY - 2016 SM - 1752-153X T1 - The effect of temperature and methanol–water mixture on pressurized hot water extraction (PHWE) of anti-HIV analogoues from Bidens pilosa TI - The effect of temperature and methanol–water mixture on pressurized hot water extraction (PHWE) of anti-HIV analogoues from Bidens pilosa UR - http://hdl.handle.net/10204/9008 ER - en_ZA


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