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Curdlan-conjugated PLGA nanoparticles possess macrophage stimulant activity and drug delivery capabilities

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dc.contributor.author Tukulula, M
dc.contributor.author Hayeshi, R
dc.contributor.author Fonteh, P
dc.contributor.author Meyer, D
dc.contributor.author Ndamase, A
dc.contributor.author Madziva, MT
dc.contributor.author Khumalo, V
dc.contributor.author Lubuschagne, P
dc.contributor.author Naicker, B
dc.contributor.author Swai, H
dc.contributor.author Dube, A
dc.date.accessioned 2015-08-17T13:33:21Z
dc.date.available 2015-08-17T13:33:21Z
dc.date.issued 2015-02
dc.identifier.citation Tukulula, M, Hayeshi, R, Fonteh, P, Meyer, D, Ndamase, A, Madziva, M.T, Khumalo, V, Lubuschagne, P, Naicker, B, Swai, H and Dube, A. 2015. Curdlan-conjugated PLGA nanoparticles possess macrophage stimulant activity and drug delivery capabilities. Pharmaceutical Research, vol. 32(8), pp 2713-2726 en_US
dc.identifier.issn 0724-8741
dc.identifier.uri http://link.springer.com/article/10.1007%2Fs11095-015-1655-9
dc.identifier.uri http://hdl.handle.net/10204/8026
dc.description Copyright: 2015 Springer. Due to copyright restrictions, the attached PDF file only contains the abstract of the full text item. For access to the full text item, please consult the publisher's website. The definitive version of the work is published in Pharmaceutical Research, vol. 32(8), pp 2713-2726 en_US
dc.description.abstract There is significant interest in the application of nanoparticles to deliver immunostimulatory signals to cells. We hypothesized that curdlan (immune stimulating polymer) could be conjugated to PLGA and nanoparticles from this copolymer would possess immunostimulatory activity, be non-cytotoxic and function as an effective sustained drug release system. en_US
dc.language.iso en en_US
dc.publisher Springer en_US
dc.relation.ispartofseries Workflow;15235
dc.subject Curdlan en_US
dc.subject Immunostimulant nanoparticles en_US
dc.subject PLGA nanoparticles en_US
dc.subject Real-time impedance measurements en_US
dc.subject Rifampicin en_US
dc.title Curdlan-conjugated PLGA nanoparticles possess macrophage stimulant activity and drug delivery capabilities en_US
dc.type Article en_US
dc.identifier.apacitation Tukulula, M., Hayeshi, R., Fonteh, P., Meyer, D., Ndamase, A., Madziva, M., ... Dube, A. (2015). Curdlan-conjugated PLGA nanoparticles possess macrophage stimulant activity and drug delivery capabilities. http://hdl.handle.net/10204/8026 en_ZA
dc.identifier.chicagocitation Tukulula, M, R Hayeshi, P Fonteh, D Meyer, A Ndamase, MT Madziva, V Khumalo, et al "Curdlan-conjugated PLGA nanoparticles possess macrophage stimulant activity and drug delivery capabilities." (2015) http://hdl.handle.net/10204/8026 en_ZA
dc.identifier.vancouvercitation Tukulula M, Hayeshi R, Fonteh P, Meyer D, Ndamase A, Madziva M, et al. Curdlan-conjugated PLGA nanoparticles possess macrophage stimulant activity and drug delivery capabilities. 2015; http://hdl.handle.net/10204/8026. en_ZA
dc.identifier.ris TY - Article AU - Tukulula, M AU - Hayeshi, R AU - Fonteh, P AU - Meyer, D AU - Ndamase, A AU - Madziva, MT AU - Khumalo, V AU - Lubuschagne, P AU - Naicker, B AU - Swai, H AU - Dube, A AB - There is significant interest in the application of nanoparticles to deliver immunostimulatory signals to cells. We hypothesized that curdlan (immune stimulating polymer) could be conjugated to PLGA and nanoparticles from this copolymer would possess immunostimulatory activity, be non-cytotoxic and function as an effective sustained drug release system. DA - 2015-02 DB - ResearchSpace DP - CSIR KW - Curdlan KW - Immunostimulant nanoparticles KW - PLGA nanoparticles KW - Real-time impedance measurements KW - Rifampicin LK - https://researchspace.csir.co.za PY - 2015 SM - 0724-8741 T1 - Curdlan-conjugated PLGA nanoparticles possess macrophage stimulant activity and drug delivery capabilities TI - Curdlan-conjugated PLGA nanoparticles possess macrophage stimulant activity and drug delivery capabilities UR - http://hdl.handle.net/10204/8026 ER - en_ZA


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