Recent functional studies have unveiled the significant role chromatin topology plays in gene regulation. Several lines of evidence suggest genes access necessary factors for transcription by forming chromatin loops. A clearer picture of the players involved in chromatin organization, including lncRNA, is emerging.
Reference:
Shibayama, Y., Fanucchi, S., Magagula, L. and Mhlanga, M.M. 2014. lncRNA and gene looping: what’s the connection?. Transcription. Vol. 5, pp1-6
Shibayama, Y., Fanucchi, S., Magagula, L., & Mhlanga, M. (2014). lncRNA and gene looping: what’s the connection?. http://hdl.handle.net/10204/7895
Shibayama, Y, Stephanie Fanucchi, L Magagula, and Musa Mhlanga "lncRNA and gene looping: what’s the connection?." (2014) http://hdl.handle.net/10204/7895
Shibayama Y, Fanucchi S, Magagula L, Mhlanga M. lncRNA and gene looping: what’s the connection?. 2014; http://hdl.handle.net/10204/7895.
