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Please use this identifier to cite or link to this item: http://hdl.handle.net/10204/5654

Title: PALM and STORM: what hides beyond the Rayleigh limit?
Authors: Henriques, R
Mhlanga, MM
Keywords: Fluorescent proteins
Super-resolution
Rayleigh
Nanoscopy
Issue Date: Jun-2009
Publisher: Wiley-VCH Verlag Berlin
Citation: Henriques, R and Mhlanga, MM. 2009. PALM and STORM: what hides beyond the Rayleigh limit? Biotechnology Journal, vol. 4(6), pp 846-857
Series/Report no.: Workflow;1898
Abstract: Super-resolution imaging allows the imaging of fluorescently labeled probes at a resolution of just tens of nanometers, surpassing classic light microscopy by at least one order of magnitude. Recent advances such as the development of photo-switchable fluorophores, high-sensitivity microscopes and single particle localization algorithms make super-resolution imaging rapidly accessible to the wider life sciences research community. As we take our first steps in deciphering the roles and behaviors of individual molecules inside their living cellular environment, a new world of research opportunities beckons. Here we discuss some of the latest developments achieved with these techniques and emerging areas where super-resolution will give fundamental new “eye” sight to cell biology.
Description: Copyright: 2009 Wiley. This is an ABSTRACT ONLY.
URI: http://www3.interscience.wiley.com/journal/122462281/abstract
http://hdl.handle.net/10204/5654
ISSN: 1860-6768
Appears in Collections:Nanotechnology
Structural biology
Systems biology
General science, engineering & technology

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