dc.contributor.author |
Swai, H
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dc.contributor.author |
Hillie, KT
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|
dc.contributor.author |
Cingo, N
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dc.contributor.author |
Kalombo, Lonji
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dc.contributor.author |
Legodi, M
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dc.contributor.author |
Semete, B
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dc.date.accessioned |
2008-12-10T12:24:12Z |
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dc.date.available |
2008-12-10T12:24:12Z |
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dc.date.issued |
2006-02 |
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dc.identifier.citation |
Swai, H, Hillie, KT, Cingo, N, Kalombo, L, Legodi, M and Semete, B. 2006. Evaluation of nano encapsulation techniques in different polymeric system for the delivery of anti-tuberculosis drugs (ATD). CSIR Research and Innovation Conference: 1st CSIR Biennial Conference, CSIR International Convention Centre Pretoria, 27-28 February 2006, pp1 |
en |
dc.identifier.uri |
http://hdl.handle.net/10204/2697
|
|
dc.description |
CSIR Research and Innovation Conference: 1st CSIR Biennial Conference, CSIR International Convention Centre Pretoria, 27-28 February 2006 |
en |
dc.description.abstract |
In this study, isoniazid, one of the most potent anti-TB drugs, was successfully encapsulated in poly (D, L- lactide-co-glycolide) (PLG) and in alginate-chitosan polymeric systems using a double-emulsion method and a cation-induced gelation method, respectively. The formulations from both systems were spray dried to obtain free-flowing powder. For the PLG system, an increase in the temperature of the inlet drying air resulted in decreased particle size, as well as increased absolute zeta potential (surface charge) and encapsulation efficiency, whereas the alginate-chitosan system showed a decrease in the particle size, absolute zeta potential and encapsulation efficiency. The PLG system gave superior results, compared with the alginate-chitosan system, in terms of size, shape, absolute zeta potential and encapsulation efficiency |
en |
dc.language.iso |
en |
en |
dc.subject |
Anti-tuberculosis drugs |
en |
dc.subject |
Nano encapsulation techniques |
en |
dc.subject |
Nanoparticles |
en |
dc.subject |
Poly (D, L-lactide-co-glycolide) |
en |
dc.subject |
ATD |
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dc.subject |
PLG |
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dc.title |
Evaluation of nano encapsulation techniques in different polymeric system for the delivery of anti-tuberculosis drugs (ATD) |
en |
dc.type |
Conference Presentation |
en |
dc.identifier.apacitation |
Swai, H., Hillie, K., Cingo, N., Kalombo, L., Legodi, M., & Semete, B. (2006). Evaluation of nano encapsulation techniques in different polymeric system for the delivery of anti-tuberculosis drugs (ATD). http://hdl.handle.net/10204/2697 |
en_ZA |
dc.identifier.chicagocitation |
Swai, H, KT Hillie, N Cingo, Lonji Kalombo, M Legodi, and B Semete. "Evaluation of nano encapsulation techniques in different polymeric system for the delivery of anti-tuberculosis drugs (ATD)." (2006): http://hdl.handle.net/10204/2697 |
en_ZA |
dc.identifier.vancouvercitation |
Swai H, Hillie K, Cingo N, Kalombo L, Legodi M, Semete B, Evaluation of nano encapsulation techniques in different polymeric system for the delivery of anti-tuberculosis drugs (ATD); 2006. http://hdl.handle.net/10204/2697 . |
en_ZA |
dc.identifier.ris |
TY - Conference Presentation
AU - Swai, H
AU - Hillie, KT
AU - Cingo, N
AU - Kalombo, Lonji
AU - Legodi, M
AU - Semete, B
AB - In this study, isoniazid, one of the most potent anti-TB drugs, was successfully encapsulated in poly (D, L- lactide-co-glycolide) (PLG) and in alginate-chitosan polymeric systems using a double-emulsion method and a cation-induced gelation method, respectively. The formulations from both systems were spray dried to obtain free-flowing powder. For the PLG system, an increase in the temperature of the inlet drying air resulted in decreased particle size, as well as increased absolute zeta potential (surface charge) and encapsulation efficiency, whereas the alginate-chitosan system showed a decrease in the particle size, absolute zeta potential and encapsulation efficiency. The PLG system gave superior results, compared with the alginate-chitosan system, in terms of size, shape, absolute zeta potential and encapsulation efficiency
DA - 2006-02
DB - ResearchSpace
DP - CSIR
KW - Anti-tuberculosis drugs
KW - Nano encapsulation techniques
KW - Nanoparticles
KW - Poly (D, L-lactide-co-glycolide)
KW - ATD
KW - PLG
LK - https://researchspace.csir.co.za
PY - 2006
T1 - Evaluation of nano encapsulation techniques in different polymeric system for the delivery of anti-tuberculosis drugs (ATD)
TI - Evaluation of nano encapsulation techniques in different polymeric system for the delivery of anti-tuberculosis drugs (ATD)
UR - http://hdl.handle.net/10204/2697
ER -
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en_ZA |