Stereochemical course of ring formation in fumitremorgin-B and verruculogen, metabolites of pennincillim-verrucuilosum-investigation into the loss of stereochemical

Please use this identifier to cite or link to this item: http://hdl.handle.net/10204/1911

Title:	Stereochemical course of ring formation in fumitremorgin-B and verruculogen, metabolites of pennincillim-verrucuilosum-investigation into the loss of stereochemical
Authors:	Vleggaar, R Horak, RM Maharaj, VJ
Keywords:	Stereochemical courses Fumitremorgin-B Verruculogen Pennicillium-metabolites Verruculosum investigations
Issue Date:	Feb-1993
Publisher:	Royal Society of Chemistry
Citation:	Vleggaar, R, et al. 1993. Stereochemical course of ring formation in fumitremorgin-B and verruculogen, metabolites of pennincillim-verrucuilosum-investigation into the loss of stereochemical. Journal of the Chemical Society-Chemical Communications, Issue 3, pp 274-275
Abstract:	Incorporation studies of [2-(2)H(3),2-(13)C].acetate and different [2H, 13C]-labelled mevalonolactones into verruculogen established the stereochemical course of ring C formation in fumitremorgin B, which results in the loss of stereochemical integrity of the C-22 methyl groups, and of the formation of the eight-membered peroxide ring at C-25 in verruculogen.
URI:	http://hdl.handle.net/10204/1911 http://hdl.handle.net/10204/1911
ISSN:	0022-4936
Appears in Collections:	Discovery chemistry General science, engineering & technology

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