The novel use of zinc chloride to catalyse the one-pot, three component synthesis of imidazo (1,2-a) pyridines for a range of substrates using either conventional heating or microwave radiation is described. This methodology afforded a number of imidazo (1,2-a) pyridines in reasonable yields and short reaction times without any significant optimization of the reaction conditions.
Reference:
Rousseau, AL, Matlaba, P and Parkinson, CJ. 2007. Multicomponent synthesis of imidazo [1,2-a] pyridines using catalytic zinc chloride. Tetrahedron Letters, Vol. 48(23), pp 4079-4082
Rousseau, A., Matlaba, P., & Parkinson, C. (2007). Multicomponent synthesis of imidazo [1,2-a] pyridines using catalytic zinc chloride. http://hdl.handle.net/10204/1312
Rousseau, AL, P Matlaba, and CJ Parkinson "Multicomponent synthesis of imidazo [1,2-a] pyridines using catalytic zinc chloride." (2007) http://hdl.handle.net/10204/1312
Rousseau A, Matlaba P, Parkinson C. Multicomponent synthesis of imidazo [1,2-a] pyridines using catalytic zinc chloride. 2007; http://hdl.handle.net/10204/1312.
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