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Browsing Research Publications/Outputs by Impact Area "Vetnry Mol Diagnostics and Vac"

Now showing items 1-11 of 11

Bioinformatics tools for gene and genome annotation analysis of microbes for synthetic biology and cancer biology applications

Author: Nweke, EE ; Suleman, Essa ; Du Plessis, M ; Thimiri Govindaraj, Deepak B Date: Aug 2021 In this book chapter, we focus on application of genome annotation and analysis of microbes for synthetic biology and cancer biology research. We particularly emphasised on application of microbial genomics in synthetic biology and cancer ... Read more
Dose immunogenicity study of a plant-produced influenza virus-like particle vaccine in layer hens

Author: Abolnik, C ; Smith, Tanya ; Wandrag, BDR ; Murphy, M ; Rautenbach, M ; Olibile, O ; O'Kennedy, Maretha M Date: Jun 2022 Avian influenza poses one of the largest known threats to global poultry production and human health, but effective poultry vaccines can reduce infections rates, production losses and prevent mortalities, and reduce viral shed to limit further ... Read more
Efficacy of a plant-produced clade 2.3.4.4 H5 influenza virus-like particle vaccine in layer hens

Author: Abolnik, C ; O’Kennedy, Martha M ; Murphy, MA ; Wandrag, BDR Date: Jun 2022 Outbreaks caused by Goose/Guangdong H5 highly pathogenic avian influenza (HPAI)-lineage viruses continue to occur in unprecedented numbers throughout Eurasia, the Middle East and Africa, causing billions of dollars in economic losses and the ... Read more
Efficacy of a plant-produced clade 2.3.4.4 H5 influenza virus-like particle vaccine in layer hens

Author: Abolnik, C ; O'Kennedy, Martha M ; Murphy, MA ; Wandrag, DBR Date: Jun 2022 Outbreaks caused by Goose/Guangdong H5 highly pathogenic avian influenza (HPAI)-lineage viruses continue to occur in unprecedented numbers throughout Eurasia, the Middle East and Africa, causing billions of dollars in economic losses and the ... Read more
Efficacy of a plant-produced infectious bronchitis virus-like particle vaccine inspecific pathogen-free chickens

Author: Sepotokele, KM ; O’Kennedy, Martha M ; Hayes, MC ; Wandrag, DBR ; Smith, P ; Abolnik, C Date: Oct 2023 Infectious bronchitis (IB) Gammacoronavirus causes a highly contagious respiratory disease in chickens that is listed by the World Organisation for Animal Health (WOAH). Its high mutation ability has resulted in numerous variants against which ... Read more c b n d
Hepatitis B core-based virus-like particles: A platform for vaccine development in plants

Author: Vahdat, MM ; Hemmati, F ; Ghorbani, A ; Rutkowska, Daria A ; Afsharifar, A ; Eskandari, MH ; Rezaei, N ; Niazi, A Date: Mar 2021 Virus-like particles (VLPs) are a class of structures formed by the self-assembly of viral capsid protein subunits and contain no infective viral genetic material. The Hepatitis B core (HBc) antigen is capable of assembling into VLPs that can ... Read more
Patents and technology transfer in CRISPR technology

Author: Grobler, Lichelle R ; Suleman, Essa ; Thimiri Govindaraj, Deepak B Date: Feb 2021 CRISPR technology has revolutionized biological research in the last decade and many academic institutions and companies have patented CRISPR systems and applications. Several patents have been filed for various applications of CRISPR in ... Read more
Plant-based production of highly potent anti-HIV antibodies with engineered posttranslational modifications

Author: Singh, Advaita Acarya ; Pooe, O ; Kwezi, Lusisizwe ; Lotter-Stark, T ; Stoychev, Stoyan H ; Alexandra, Kabamba B ; Gerber, Isak B ; Bhiman, JN ; Vorster, J ; Pauly, M ; Zeitlin, L ; Whaley, K ; Mach, L ; Steinkellner, H ; Morris, L ; Tsekoa, Tsepo L ; Chikwamba, Rachel K Date: Apr 2020 Broadly neutralising antibodies (bNAbs) against human immunodeficiency virus type 1 (HIV-1), such as CAP256-VRC26 are being developed for HIV prevention and treatment. These Abs carry a unique but crucial post-translational modification (PTM), ... Read more
Plant-derived VLP: A worthy platform to produce vaccine against SARS-CoV-2

Author: Hemmati, F ; Hemmati-Dinarvand, M ; Karimzade, M ; Rutkowska, Daria A ; Eskandari, MH ; Khanizadeh, S ; Afsharifar, A Date: Nov 2021 After its emergence in late 2019 SARS-CoV-2 was declared a pandemic by the World Health Organization on 11 March 2020 and has claimed more than 2.8 million lives. There has been a massive global effort to develop vaccines against SARS-CoV-2 ... Read more
The production of Newcastle disease virus-like particles in Nicotiana benthamiana as potential vaccines

Author: Smith, Tanya ; O’Kennedy, Martha M ; Ross, CS ; Lewis, NS ; Abolnik, C Date: Feb 2023 Newcastle disease (ND) is a highly contagious viral respiratory and neurological disease that has a severe impact on poultry production worldwide. In the present study, an expression platform was established for the transient production in ... Read more
Protective immunity of plant-produced African horse sickness virus serotype 5 chimaeric virus-like particles (VLPs) and viral protein 2 (VP2) vaccines in IFNAR-/- mice

Author: O'Kennedy, Maretha M ; Coetzee, P ; Koekemoer, O ; Du Plessis, L ; Lourens, CW ; Kwezi, Lusisizwe ; Du Preez, Ilse ; Mamputha, Sipho ; Rutkowska, Daria A ; Lemmer, Yolandy Date: Aug 2022 Next generation vaccines have the capability to contribute to and revolutionise the veterinary vaccine industry. African horse sickness (AHS) is caused by an arbovirus infection and is characterised by respiratory distress and/or cardiovascular ... Read more

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Browsing Research Publications/Outputs by Impact Area "Vetnry Mol Diagnostics and Vac"

Browsing Research Publications/Outputs by Impact Area "Vetnry Mol Diagnostics and Vac"

Browse

All of ResearchSpace

This Community

Quick Links

Legislation and compliance

General Enquiries

Social Connect