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dc.contributor.author Fatoki, OS
dc.contributor.author Opeolu, BO
dc.contributor.author Genthe, Bettina
dc.contributor.author Olatunji, OS
dc.date.accessioned 2019-03-05T10:03:08Z
dc.date.available 2019-03-05T10:03:08Z
dc.date.issued 2018-12
dc.identifier.citation Fatoki, O.S. et al. 2018. Multi-residue method for the determination of selected veterinary pharmaceutical residues in surface water around Livestock Agricultural farms. Heliyon, vol. 4(12): 1-16 en_US
dc.identifier.issn 2405-8440
dc.identifier.uri Doi: 10.1016/j.heliyon.2018.e01066
dc.identifier.uri https://www.sciencedirect.com/science/article/pii/S2405844018304195?via%3Dihub
dc.identifier.uri http://hdl.handle.net/10204/10742
dc.description Open access article published in Heliyon, vol. 4(12): 1-16 en_US
dc.description.abstract A multi-residue method for the determination of the occurrence and prevalence levels of selected veterinary pharmaceutical residues in surface water was developed on a high performance liquid chromatography coupled to ultraviolet-visible (HPLC-UV) detector, and tested with the intent of profiling their distribution. The limit of detection (LOD) and limit of quantitation (LOQ) achieved for the selected pharmaceuticals; acetaminophen, diclofenac, salicylic acid, tetracycline, chloramphenicol, ciprofloxacin, bisphenol-A, 17ß-estradiol, estriol, and ivermectin ranged between 0.06-3.45 µg L-1 and 0.17-10.35 µg L-1 respectively. Other International Conference on Harmonization (ICH) parameters for validation of analytical procedures were also evaluated and discussed. Pharmaceutical residues were recovered from surface water samples collected from around livestock farms in Cape Town, South Africa by solid phase extraction (SPE), and thereafter separated and quantified using a validated method on a HPLC-UV-detector. Most frequently detected residues were: acetaminophen (56%), diclofenac (53), tetracycline (72%), 17ß-estradiol (73%); chloramphenicol (68%), and salicylic acid (67%), with significantly high (p > 0.05) spatial variability in the concentration distributions of the pharmaceuticals in the surface waters. en_US
dc.language.iso en en_US
dc.publisher Elsevier en_US
dc.relation.ispartofseries Worklist;22077
dc.subject Analytical chemistry en_US
dc.subject Environmental science en_US
dc.subject Veterinary pharmaceutical residues en_US
dc.subject Pharmaceutical residues en_US
dc.title Multi-residue method for the determination of selected veterinary pharmaceutical residues in surface water around Livestock Agricultural farms en_US
dc.type Article en_US


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