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Browsing by Author "Naidoo, Saloshnee"

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Design and formulation of nano-sized spray dried Efavirenz-Part 1: Influence of formulation parameters

Author: Tshweu, L ; Katata, L ; Naidoo, Saloshnee ; Kalombo, Lonji ; Swai, H Date: Oct 2012 AIDS kills over 1.5 million people a year globally. Current HIV drugs pose many challenges. This presentation shows that nano-encapsulation of HIV drugs achieves controlled and steady drug release, and reduced dosing frequency. Read more
Design and formulation of nano-sized spray dried efavirenz. Part I: Influence of formulation parameters

Author: Katata, L ; Tshweu, L ; Naidoo, Saloshnee ; Kalombo, Lonji ; Swai, H Date: Oct 2012 Efavirenz (EFV) is one of the first-line antiretroviral drugs recommended by the World Health Organisation for treating HIV. It is a hydrophobic drug that suffers from low aqueous solubility (4 lg/mL), which leads to a limited oral absorption ... Read more
Novel nanoparticles for Tuberculosis chemotherapy

Author: Semete, B ; Kalombo, Lonji ; Chelule, P ; Benadie, Y ; Booysen, L ; Katata, L ; Naidoo, Saloshnee ; Swai, H Date: Nov 2008 Current therapeutic management of tuberculosis is inadequate due to non-compliance, lengthy course of treatment and drug- related side effects. In order to address these setbacks, the authors are developing a nanotechnology drug delivery ... Read more
Potential of improving the treatment of tuberculosis through nanomedicine

Author: Semete, B ; Kalombo, Lonji ; Katata, L ; Chelule, P ; Booysen, L ; Lemmer, Yolandy ; Naidoo, Saloshnee ; Ramalapa, B ; Hayeshi, R ; Swai, HS Date: Mar 2012 Current treatment of tuberculosis is inadequate due to lengthy treatment course and drug-related toxicity. To address these setbacks, we developed a nanotechnology drug delivery system that can be administered in a single dose that maintains ... Read more
Preparation of rifampicin/poly(d,l-lactice) nanoparticles for sustained release by supercritical assisted atomization technique

Author: Labuschagne, Philip W ; Adami, R ; Liparoti, S ; Naidoo, Saloshnee ; Swai, H ; Reverchon, E Date: Nov 2014 In this work supercritical assisted atomization (SAA) process was used for the co-precipitation of poly(d,l-lactide) (PDLLA) and rifampicin (RIF) as nanoparticles for sustained release applications. The effect of the variation of PDLLA/RIF ... Read more

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Browsing by Author "Naidoo, Saloshnee"

Browsing by Author "Naidoo, Saloshnee"

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