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Browsing by Subject "Neurodegenerative diseases"

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Discovery of novel Acetylcholinesterase inhibitors by virtual screening, in vitro screening, and molecular dynamics simulations

Author: Van van der Westhuizen, Johan C ; Stander, A ; Riley, DL ; Panayides, Jenny-Lee Date: Mar 2022 Alzheimer's disease is the most common neurodegenerative disease and currently poses a significant socioeconomic problem. This study describes the uses of computer-aided drug discovery techniques to identify novel inhibitors of acetylcholinesterase, ... Read more
Medicinal plants with cholinesterase inhibitory activity: a review

Author: Adewusi, EA ; Moodley, N ; Steenkamp, V Date: Dec 2010 Alzheimer’s disease (AD), a common neurodegenerative disease, is characterized by low levels in the brain of the neurotransmitter, acetylcholine (ACh). Clinical treatment of this disease is palliative and relies mostly on enhancing cholinergic ... Read more

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Browsing by Subject "Neurodegenerative diseases"

Browsing by Subject "Neurodegenerative diseases"

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All of ResearchSpace

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