Author:Adewusi, EA; Fouché, Gerda; Steenkamp, VDate:2013Amyloid-beta peptide (Aß) is implicated in the pathogenesis of Alzheimer’s disease (AD), a neurodegenerative disorder. This study was designed to determine the effect of four medicinal plants used to treat neurodegenerative diseases on ...Read more
Author:Marondedze, EF; Govender, Krishna K; Govender, PPDate:Dec 2020Currently, only three molecules, flutemetamol, florbetaben and florbetapir, have been approved for clinical use towards the definitive diagnosis of Alzheimer’s disease (AD). Despite the clinically approved drugs’ advantages, there still exists ...Read more
Author:Adewusi, EA; Moodley, N; Steenkamp, VDate:Dec 2010Alzheimer’s disease (AD), a common neurodegenerative disease, is characterized by low levels in the brain of the neurotransmitter, acetylcholine (ACh). Clinical treatment of this disease is palliative and relies mostly on enhancing cholinergic ...Read more