Author:Shibayama, Y; Fanucchi, Stephanie; Magagula, L; Mhlanga, MusaDate:May 2014Recent functional studies have unveiled the significant role chromatin topology plays in gene regulation. Several lines of evidence suggest genes access necessary factors for transcription by forming chromatin loops. A clearer picture of the ...Read more
Author:Shibayama, Y; Fanucchi, Stephanie; Mhlanga, MusaDate:2017Enhancers are principal regulators that allow spatiotemporal tissue-specifi c control of gene expression. While mounting evidence suggests that enhancer-derived long noncoding RNAs (long ncRNAs), including enhancer RNAs (eRNAs), are an important ...Read more