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Browsing by Subject "Human immunodeficiency virus"

Now showing items 1-11 of 11

The combination of low level laser therapy and efavirenz drastically reduces HIV infection in TZM-bl cells

Author: Lugongolo, Masixole Y ; Manoto, Sello L ; Ombinda-Lemboumba, Saturnin ; Maaza, M ; Mthunzi-Kufa, Patience Date: Jun 2020 Human immunodeficiency virus (HIV) infection remains a global health challenge despite the use of antiretroviral therapy, which has led to a significant decline in the mortality rates. Owing to the unavailability of an effective treatment to ... Read more
Examining HIV infected cells using optical trapping and Raman spectroscopy

Author: Lugongolo, Masixole Y ; Ombinda-Lemboumba, Saturnin ; Manoto, Sello L ; Mthunzi-Kufa, Patience Date: Sep 2021 Manipulation of biological cells using optical trapping is a non-invasive approach in which individual living cells are examined without causing any damage because there is no direct mechanical contact with cells. Optical trapping uses a ... Read more
Examining HIV infected cells using optical trapping and Raman spectroscopy

Author: Lugongolo, Masixole Y ; Ombinda-Lemboumba, Saturnin ; Manoto, Sello L ; Mthunzi-Kufa, Patience Date: Sep 2021 Manipulation of biological cells using optical trapping is a non-invasive approach in which individual living cells are examined without causing any damage because there is no direct mechanical contact with cells. Optical trapping uses a ... Read more
Exploring optical spectroscopic techniques and nanomaterials for virus detection

Author: Manoto, Sello L ; El-Hussein, A ; Malabi, Rudzani ; Thobakgale, Setumo L ; Ombinda-Lemboumba, Saturnin ; Attia, YA ; Kasem, MA ; Mthunzi-Kufa, Patience Date: Aug 2020 Viral infections pose significant health challenges globally by affecting millions of people worldwide and consequently resulting in a negative impact on both socioeconomic development and health. Corona virus disease 2019 (COVID-19) is a ... Read more
Expression of HIV-1 antigens in plants as potential subunit vaccines

Author: Meyers, A ; Chakauya, E ; Shepard, E ; Tanzer, FL ; Lynch, A ; Williamson, A ; Rybicki, EP Date: 23 Jun 2008 Human immunodeficiency virus type 1 (HIV-1) has infected more than 40 million people worldwide, mainly in sub-Saharan Africa. The high prevalence of HIV-1 subtype C in southern Africa necessitates the development of cheap, effective vaccines. ... Read more
Impact of incident and prevalent herpes simplex virus-2 infection on the incidence of HIV-1 infection among commercial sex workers in South Africa

Author: Ramjee, G ; Williams, B ; Gouws, E ; Van Dyck, E ; De Deken, B ; Karim, SA Date: 01 Jul 2005 This study investigated the impact of prevalent and incident HSV-2 infection on the incidence of HIV-1 infection in a cohort of female commercial sex workers in KwaZulu-Natal, South Africa. Prior to a vaginal microbicide trial, 416 women were ... Read more
Natural history of HIV/AIDS in a major goldmining centre in South Africa: results of a biomedical and social survey

Author: Gilgen, D ; Williams, BG ; MacPhail, C ; Van Dam, CJ ; Campbell, C ; Ballard, RC ; Taljaard, D Date: Sep 2001 This paper presents the results of a cross-sectional biomedical and social survey, conducted in a major gold mining centre with a high prevalence of HIV infection. It also provides the baseline data for a comprehensive intervention programme. ... Read more
Point of care diagnostics for HIV in resource limited settings: an overview

Author: Manoto, Sello L ; Lugongolo, Masixole Y ; Govender, Ureshnie ; Mthunzi-Kufa, Patience Date: Mar 2018 Human immunodeficiency virus (HIV) is a global health problem. Early diagnosis, rapid antiretroviral therapy (ART) initiation and monitoring of viral load are the key strategies for effective HIV management. Many people in resource limited ... Read more
Potential of RNA aptamers in the prevention of HIV-1 subtype C infections

Author: London, GM ; Khati, M ; Mayosi, B Date: Oct 2014 Compounds that have been used to prevent human immunodeficiency virus type-I (HIV-1) infections include synthetic chemicals, plant extras and monoclonal antibodies. Although most of these compounds have potent antiviral activity, they often ... Read more
Recognition of anti-mycolic acid antibody at self-assembled mycolic acid antigens on a gold electrode: a potential impedimetric immunosensing platform for active tuberculosis

Author: Mathebula, NS ; Pillay, J ; Toschi, G ; Verschoor, JA ; Ozoemena, KI Date: 2009 Electrochemical impedimetric recognition by anti-mycolic acid antibodies, present in tuberculosis (TB)-positive human serum co-infected with human immunodeficiency virus (HIV), of mycolic acids (MA) integrated into a self-assembled monolayer ... Read more
Transient proteolysis reduction of Nicotiana benthamiana-produced CAP256 broadly neutralizing antibodies using CRISPR/Cas9

Author: Singh, Advaita A ; Pillay, Priyen ; Naicker, Previn ; Alexandre, Kabamba B ; Malatji, Kanyane ; Mach, L ; Steinkellner, H ; Vorster, J ; Chikwamba, Rachel K ; Tsekoa, Tsepo L Date: Aug 2022 The hypersensitive response is elicited by Agrobacterium infiltration of Nicotiana benthamiana, including the induction and accumulation of pathogenesis-related proteins, such as proteases. This includes the induction of the expression of ... Read more

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Browsing by Subject "Human immunodeficiency virus"

Browsing by Subject "Human immunodeficiency virus"

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