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Please use this identifier to cite or link to this item:
http://hdl.handle.net/10204/3582
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| Title: | Recognition of anti-mycolic acid antibody at self-assembled mycolic acid antigens on a gold electrode: a potential impedimetric immunosensing platform for active tuberculosis |
| Authors: | Mathebula, NS
Pillay, J
Toschi, G
Verschoor, JA
Ozoemena, KI |
| Keywords: | Anti-mycolic acid
Tuberculosis treatment
Gold electrode
Electrochemical impedimetric
Serum dilution
Chemical Communications
Human immunodeficiency virus
Mycolic acid
Chemistry |
| Issue Date: | 2009 |
| Publisher: | The Royal Society of Chemistry |
| Citation: | Mathebula, NS, Pillay, J, Toschi, G, Verschoor, JA and Ozoemena, KI. 2009. Recognition of anti-mycolic acid antibody at self-assembled mycolic acid antigens on a gold electrode: a potential impedimetric immunosensing platform for active tuberculosis. Chemical Communications, Vol. 23. pp 3345-3347 |
| Abstract: | Electrochemical impedimetric recognition by anti-mycolic acid antibodies, present in tuberculosis (TB)-positive human serum co-infected with human immunodeficiency virus (HIV), of mycolic acids (MA) integrated into a self-assembled monolayer of N-(2-mercaptoethyl)octadecanamide on a gold electrode is described, proving that the MA-based electrode can satisfactorily discriminate between a TB-positive and a TB-negative serum, thus offering promise as a potential impedimetric immunosensing platform for active tuberculosis. |
| Description: | Copyright: 2009 The Royal Society of Chemistry |
| URI: | http://hdl.handle.net/10204/3582 |
| ISBN: | 1359-7345 |
| Appears in Collections: | Water resources and human health
Nanotechnology
Analytical science
Structural biology
General science, engineering & technology
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