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Please use this identifier to cite or link to this item: http://hdl.handle.net/10204/3582

Title: Recognition of anti-mycolic acid antibody at self-assembled mycolic acid antigens on a gold electrode: a potential impedimetric immunosensing platform for active tuberculosis
Authors: Mathebula, NS
Pillay, J
Toschi, G
Verschoor, JA
Ozoemena, KI
Keywords: Anti-mycolic acid
Tuberculosis treatment
Gold electrode
Electrochemical impedimetric
Serum dilution
Chemical Communications
Human immunodeficiency virus
Mycolic acid
Chemistry
Issue Date: 2009
Publisher: The Royal Society of Chemistry
Citation: Mathebula, NS, Pillay, J, Toschi, G, Verschoor, JA and Ozoemena, KI. 2009. Recognition of anti-mycolic acid antibody at self-assembled mycolic acid antigens on a gold electrode: a potential impedimetric immunosensing platform for active tuberculosis. Chemical Communications, Vol. 23. pp 3345-3347
Abstract: Electrochemical impedimetric recognition by anti-mycolic acid antibodies, present in tuberculosis (TB)-positive human serum co-infected with human immunodeficiency virus (HIV), of mycolic acids (MA) integrated into a self-assembled monolayer of N-(2-mercaptoethyl)octadecanamide on a gold electrode is described, proving that the MA-based electrode can satisfactorily discriminate between a TB-positive and a TB-negative serum, thus offering promise as a potential impedimetric immunosensing platform for active tuberculosis.
Description: Copyright: 2009 The Royal Society of Chemistry
URI: http://hdl.handle.net/10204/3582
ISBN: 1359-7345
Appears in Collections:Water resources and human health
Nanotechnology
Analytical science
Structural biology
General science, engineering & technology

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