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Palladium-catalysed arylation of acetoacetate esters to yield 2-arylacetic acid esters

Author: Zeevaart, JG ; Parkinson, CJ ; De Koning, CB Date: 24 May 2004 The coupling reaction between ethyl acetoacetate and a number of aryl halides in the presence of palladium acetate, a bulky and electron rich phosphine and K3PO4 is described. The arylated acetoacetate ester is de-acylated under the reaction ... Read more

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Browsing by Subject "Enolate arylation"

Browsing by Subject "Enolate arylation"

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