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Browsing by Author "Shibayama, Y"

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Chromosomal contact permits transcription between coregulated genes

Author: Fanucchi, Stephanie ; Shibayama, Y ; Burd, S ; Weinberg, MS ; Mhlanga, Musa Date: Oct 2013 Transcription of coregulated genes occurs in the context of long-range chromosomal contacts that form multigene complexes. Such contacts and transcription are lost in knockout studies of transcription factors and structural chromatin proteins. ... Read more
lncRNA and gene looping: what’s the connection?

Author: Shibayama, Y ; Fanucchi, Stephanie ; Magagula, L ; Mhlanga, Musa Date: May 2014 Recent functional studies have unveiled the significant role chromatin topology plays in gene regulation. Several lines of evidence suggest genes access necessary factors for transcription by forming chromatin loops. A clearer picture of the ... Read more
A simple recipe for the non-expert bioinformaticist for building experimentally-testable hypotheses for proteins with no known homologs

Author: Zawaira, A ; Shibayama, Y Date: Dec 2012 The study of the protein-protein interactions (PPIs) of unique ORFs is a strategy for deciphering the biological roles of unique ORFs of interest. For uniform reference, we define unique ORFs as those for which no matching protein is found ... Read more
Visualization of enhancer-derived noncoding RNA

Author: Shibayama, Y ; Fanucchi, Stephanie ; Mhlanga, Musa Date: 2017 Enhancers are principal regulators that allow spatiotemporal tissue-specifi c control of gene expression. While mounting evidence suggests that enhancer-derived long noncoding RNAs (long ncRNAs), including enhancer RNAs (eRNAs), are an important ... Read more

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Browsing by Author "Shibayama, Y"

Browsing by Author "Shibayama, Y"

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All of ResearchSpace

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