Stark, TChakauya, EKabamba, AMorris, LRybicki, EChikwamba, Rachel K2010-10-082010-10-082010-08Stark, T, Chakauya, E, Kabamba, A et al. 2010. Effect of expressing an anti-HIV lectin, Griffithsin, in different plant cellular compartments. CSIR 3rd Biennial Conference 2010. Science Real and Relevant. CSIR International Convention Centre, Pretoria, South Africa, 30 August – 01 September 2010, pp 18http://hdl.handle.net/10204/4457CSIR 3rd Biennial Conference. Science Real and Relevant, CSIR International Convention Centre, Pretoria, 30 August – 1 September 2010Sub-Saharan Africa remains the region most heavily affected by HIV, and the majority of new infections from heterosexual contact are in women. Griffithsin (GRFT), a lectin isolated from the red algae Griffithsia, has shown extreme potency against the Human Immunodeficiency Virus (HIV) in vitro in very low quantities. The molecular target of GRFT is the high mannose residues on the viral gp120 coat protein. Low cost production of GRFT and other anti-HIV drugs at minimal costs is crucial seeing that the high demand for anti-HIV drugs reside in poor developing countries.enGriffithsinAnti-HIV lectinPharmaceuticalsTherapeutic moleculesSubcellularCSIR Conference 2010Conference PresentationStark, T., Chakauya, E., Kabamba, A., Morris, L., Rybicki, E., & Chikwamba, R. K. (2010). Effect of expressing an anti-HIV lectin, Griffithsin, in different plant cellular compartments. http://hdl.handle.net/10204/4457Stark, T, E Chakauya, A Kabamba, L Morris, E Rybicki, and Rachel K Chikwamba. "Effect of expressing an anti-HIV lectin, Griffithsin, in different plant cellular compartments." (2010): http://hdl.handle.net/10204/4457Stark T, Chakauya E, Kabamba A, Morris L, Rybicki E, Chikwamba RK, Effect of expressing an anti-HIV lectin, Griffithsin, in different plant cellular compartments; 2010. http://hdl.handle.net/10204/4457 .TY - Conference Presentation AU - Stark, T AU - Chakauya, E AU - Kabamba, A AU - Morris, L AU - Rybicki, E AU - Chikwamba, Rachel K AB - Sub-Saharan Africa remains the region most heavily affected by HIV, and the majority of new infections from heterosexual contact are in women. Griffithsin (GRFT), a lectin isolated from the red algae Griffithsia, has shown extreme potency against the Human Immunodeficiency Virus (HIV) in vitro in very low quantities. The molecular target of GRFT is the high mannose residues on the viral gp120 coat protein. Low cost production of GRFT and other anti-HIV drugs at minimal costs is crucial seeing that the high demand for anti-HIV drugs reside in poor developing countries. DA - 2010-08 DB - ResearchSpace DP - CSIR KW - Griffithsin KW - Anti-HIV lectin KW - Pharmaceuticals KW - Therapeutic molecules KW - Subcellular KW - CSIR Conference 2010 LK - https://researchspace.csir.co.za PY - 2010 T1 - Effect of expressing an anti-HIV lectin, Griffithsin, in different plant cellular compartments TI - Effect of expressing an anti-HIV lectin, Griffithsin, in different plant cellular compartments UR - http://hdl.handle.net/10204/4457 ER -