Malatjie, Patrick GFaniso-Myaka, Zimbini2026-01-222026-01-222025-112261-236Xhttps://doi.org/10.1051/matecconf/202541706017http://hdl.handle.net/10204/14637The Hypertext Transfer Protocol (HTTP) has become a fundamental component for client-server communication in web applications. This paper investigates the performance and suitability of HTTP request handling in three popular Python frameworks: Flask, Django, and FastAPI. Through comparative analysis, we evaluate the effectiveness of each framework based on speed, scalability, and ease of implementation, providing recommendations for its use in various development scenarios.FulltextenHypertext Transfer ProtocolHTTPPython frameworksFlaskDjangoFastAPIArticleN/A