Sagandira, Cloudius R2025-09-082025-09-082025-082730-664Xhttps://doi.org/10.1038/s43856-025-01080-6http://hdl.handle.net/10204/14390After decades of dependence on imported Active Pharmaceutical Ingredients (APIs) and multilateral aid, Africa faces a critical turning point, seeking to assert control over its health and economic future. Here we discuss how agile local API manufacturing offers a strategic solution to enhance health and economic security, transforming Africa’s pharmaceutical landscape for sustainable medicine access.FulltextenActive Pharmaceutical IngredientsAPIsDrug manufacturingAgile local manufacturing of active pharmaceutical ingredients in Africa could improve health security and economic growthArticlen/a