Mashingaidze, FChoonara, YEKumar, PDu Toit, LCMaharaj, VBuchmann, ENdesendo, VMKPillay, V2013-09-302013-09-302013-09Mashingaidze, F, Choonara, Y.E, Kumar, P, du Toit L.C, Maharaj, V, Buchmann, E, Ndesendo, V.M.K and Pillay, V. 2013. Exploration of the biomacromolecular interactions of an interpenetrating proteo-saccharide hydrogel network at the mucosal interface. Journal of Biomedical Materials Research Part A, pp 1-141549-3296http://onlinelibrary.wiley.com/doi/10.1002/jbm.a.34664/pdfhttp://hdl.handle.net/10204/6966Copyright: 2013 Wiley-Blackwell This is an ABSTRACT ONLY. The definitive version is published in Journal of Biomedical Materials Research Part A, pp 1-14The relationship between mucin (MUC) and pectin (PEC) was explored in an attempt to understand the biomacro-molecular interactions that occur at mucosal surfaces when mucus membranes are exposed to PEC-based materials. These interactions were explored through techniques, such as attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy, SEM imagery of lyophilized MUC–PEC blends, thermodynamic analysis, rheology investigations, and in silico static lattice atomistic simulations using a molecular mechanics energy relationships (MMER) approach.enPectinMucinMacromolecular interactionSynergistic enhancement in rheologyMolecular mechanicsEnergy relationshipsExploration of the biomacromolecular interactions of an interpenetrating proteo-saccharide hydrogel network at the mucosal interfaceArticleMashingaidze, F., Choonara, Y., Kumar, P., Du Toit, L., Maharaj, V., Buchmann, E., ... Pillay, V. (2013). Exploration of the biomacromolecular interactions of an interpenetrating proteo-saccharide hydrogel network at the mucosal interface. http://hdl.handle.net/10204/6966Mashingaidze, F, YE Choonara, P Kumar, LC Du Toit, V Maharaj, E Buchmann, VMK Ndesendo, and V Pillay "Exploration of the biomacromolecular interactions of an interpenetrating proteo-saccharide hydrogel network at the mucosal interface." (2013) http://hdl.handle.net/10204/6966Mashingaidze F, Choonara Y, Kumar P, Du Toit L, Maharaj V, Buchmann E, et al. Exploration of the biomacromolecular interactions of an interpenetrating proteo-saccharide hydrogel network at the mucosal interface. 2013; http://hdl.handle.net/10204/6966.TY - Article AU - Mashingaidze, F AU - Choonara, YE AU - Kumar, P AU - Du Toit, LC AU - Maharaj, V AU - Buchmann, E AU - Ndesendo, VMK AU - Pillay, V AB - The relationship between mucin (MUC) and pectin (PEC) was explored in an attempt to understand the biomacro-molecular interactions that occur at mucosal surfaces when mucus membranes are exposed to PEC-based materials. These interactions were explored through techniques, such as attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy, SEM imagery of lyophilized MUC–PEC blends, thermodynamic analysis, rheology investigations, and in silico static lattice atomistic simulations using a molecular mechanics energy relationships (MMER) approach. DA - 2013-09 DB - ResearchSpace DP - CSIR KW - Pectin KW - Mucin KW - Macromolecular interaction KW - Synergistic enhancement in rheology KW - Molecular mechanics KW - Energy relationships LK - https://researchspace.csir.co.za PY - 2013 SM - 1549-3296 T1 - Exploration of the biomacromolecular interactions of an interpenetrating proteo-saccharide hydrogel network at the mucosal interface TI - Exploration of the biomacromolecular interactions of an interpenetrating proteo-saccharide hydrogel network at the mucosal interface UR - http://hdl.handle.net/10204/6966 ER -