Moolman, SLabuschagne, Philip WThantsha, MSVan der Merwe, TLCloete, TE2008-12-122008-12-122006-02-27Moolman, S, Labuschagne, PW, Thantsha, MS, Van der Merwe, TL, and Cloete, TE. 2006. Formation of an interpolymer complex in supercritical carbon dioxide and its application in the encapsulation of probiotics. CSIR Research and Innovation Conference: 1st CSIR Biennial Conference, CSIR International Convention Centre Pretoria, 27-28 February 2006, pp 37http://hdl.handle.net/10204/2737CSIR Research and Innovation Conference: 1st CSIR Biennial Conference, CSIR International Convention Centre Pretoria, 27-28 February 2006Traditional encapsulation methods present difficulties for sensitive actives such as probiotics, due to exposure to water/solvents, heat, oxygen, etc. The authors present a novel encapsulation technology utilising the formation of an interpolymer complex in a supercritical carbon dioxide environment. Interpolymer complex formation was confirmed through FTIR and moisture absorption studies. Polymer liquefaction and release of encapsulated probiotics were studied with SEM. Indomethacin and B. longum were encapsulated using the method, with poly(vinyl pyrrolidone) and poly(vinyl acetate-co-crotonic acid) as interpolymer complex. The polymer system provides protection at low pH, while releasing at higher pH. Potential applications include encapsulation of sensitive actives in the food and pharmaceutical industryenInterpolymer complexesPolymersSupercritical fluidsSupercritical carbon dioxideProbiotics encapsulationConference PresentationMoolman, S., Labuschagne, P. W., Thantsha, M., Van der Merwe, T., & Cloete, T. (2006). Formation of an interpolymer complex in supercritical carbon dioxide and its application in the encapsulation of probiotics. http://hdl.handle.net/10204/2737Moolman, S, Philip W Labuschagne, MS Thantsha, TL Van der Merwe, and TE Cloete. "Formation of an interpolymer complex in supercritical carbon dioxide and its application in the encapsulation of probiotics." (2006): http://hdl.handle.net/10204/2737Moolman S, Labuschagne PW, Thantsha M, Van der Merwe T, Cloete T, Formation of an interpolymer complex in supercritical carbon dioxide and its application in the encapsulation of probiotics; 2006. http://hdl.handle.net/10204/2737 .TY - Conference Presentation AU - Moolman, S AU - Labuschagne, Philip W AU - Thantsha, MS AU - Van der Merwe, TL AU - Cloete, TE AB - Traditional encapsulation methods present difficulties for sensitive actives such as probiotics, due to exposure to water/solvents, heat, oxygen, etc. The authors present a novel encapsulation technology utilising the formation of an interpolymer complex in a supercritical carbon dioxide environment. Interpolymer complex formation was confirmed through FTIR and moisture absorption studies. Polymer liquefaction and release of encapsulated probiotics were studied with SEM. Indomethacin and B. longum were encapsulated using the method, with poly(vinyl pyrrolidone) and poly(vinyl acetate-co-crotonic acid) as interpolymer complex. The polymer system provides protection at low pH, while releasing at higher pH. Potential applications include encapsulation of sensitive actives in the food and pharmaceutical industry DA - 2006-02-27 DB - ResearchSpace DP - CSIR KW - Interpolymer complexes KW - Polymers KW - Supercritical fluids KW - Supercritical carbon dioxide KW - Probiotics encapsulation LK - https://researchspace.csir.co.za PY - 2006 T1 - Formation of an interpolymer complex in supercritical carbon dioxide and its application in the encapsulation of probiotics TI - Formation of an interpolymer complex in supercritical carbon dioxide and its application in the encapsulation of probiotics UR - http://hdl.handle.net/10204/2737 ER -