Smit, Jacoba EHanekom, THanekom, JJ2009-09-012009-09-012009-03Smit, JE, Hanekom. T and Hanekom, JJ. 2009. Estimation of stimulus attenuation in cochlear implants. Journal of Neuroscience Methods, Vol. 180. pp 363-3730165-0270http://hdl.handle.net/10204/3559Pre-print versionNeural excitation profile widths at the neural level, for monopolar stimulation with Nucleus straight and contour arrays respectively, were simulated using a combined volume-conduction-neural model. The electrically evoked compound action potential profile widths at the electrode array level were calculated with a simple approximation method employing stimulus attenuation inside the cochlear duct, and the results compared to profile width data from literature. The objective of the article is to develop a simple method to estimate stimulus attenuation values by calculating the values that best fit the modelled excitation profile widths to the measured evoked compound action potential profile widths. Results indicate that the modelled excitation profile widths decrease with increasing stimulus attenuation. However, fitting of modelled excitation profile widths to measured evoked compound action potential profile widths show that different stimulus attenuation values are needed for different stimulation levels. It is suggested that the proposed simple model can provide an estimate of stimulus attenuation by calculating the value of the parameter that produces the best fit to experimental data in specific human subjects.enStimulus attenuationCochlear implantsLength constantcomputational modelEvoked compound action potentialNeural excitation spreadHuman auditory nerve fibreANFsNeuroscienceArticleSmit, J. E., Hanekom, T., & Hanekom, J. (2009). Estimation of stimulus attenuation in cochlear implants. http://hdl.handle.net/10204/3559Smit, Jacoba E, T Hanekom, and JJ Hanekom "Estimation of stimulus attenuation in cochlear implants." (2009) http://hdl.handle.net/10204/3559Smit JE, Hanekom T, Hanekom J. Estimation of stimulus attenuation in cochlear implants. 2009; http://hdl.handle.net/10204/3559.TY - Article AU - Smit, Jacoba E AU - Hanekom, T AU - Hanekom, JJ AB - Neural excitation profile widths at the neural level, for monopolar stimulation with Nucleus straight and contour arrays respectively, were simulated using a combined volume-conduction-neural model. The electrically evoked compound action potential profile widths at the electrode array level were calculated with a simple approximation method employing stimulus attenuation inside the cochlear duct, and the results compared to profile width data from literature. The objective of the article is to develop a simple method to estimate stimulus attenuation values by calculating the values that best fit the modelled excitation profile widths to the measured evoked compound action potential profile widths. Results indicate that the modelled excitation profile widths decrease with increasing stimulus attenuation. However, fitting of modelled excitation profile widths to measured evoked compound action potential profile widths show that different stimulus attenuation values are needed for different stimulation levels. It is suggested that the proposed simple model can provide an estimate of stimulus attenuation by calculating the value of the parameter that produces the best fit to experimental data in specific human subjects. DA - 2009-03 DB - ResearchSpace DP - CSIR KW - Stimulus attenuation KW - Cochlear implants KW - Length constant KW - computational model KW - Evoked compound action potential KW - Neural excitation spread KW - Human auditory nerve fibre KW - ANFs KW - Neuroscience LK - https://researchspace.csir.co.za PY - 2009 SM - 0165-0270 T1 - Estimation of stimulus attenuation in cochlear implants TI - Estimation of stimulus attenuation in cochlear implants UR - http://hdl.handle.net/10204/3559 ER -