Pillay, PMaharaj, VJSmith, PJ2009-05-112009-05-112008-10Pillay, P, Maharaj, VJ and Smith, PJ. 2008. Investigating South African plants as a source of new antimalarial drugs. Journal of Ethnopharmacology, Vol. 119(3), pp 1-270378-8741http://hdl.handle.net/10204/3367Author Posting. Copyright Elsevier, 2008. This is the author's version of the work. It is posted here by permission of Elsevier for personal use, not for redistributionBased on the historical success of natural products as antimalarial drugs and the urgent need for new antimalarials, a number of South African medicinal plants have been evaluated for their antimalarial properties. This paper reviews the major studies conducted and their findings. Overall three ethnobotanical screening programmes have been conducted on South African plants and there have been three studies adopting a more direct approach where plants within a particular genus were screened for antiplasmodial activity. The paper also summarizes antimalarial plants, which were studied individually, as well as the bioactive molecules identified from selected active plant extractsenMedicinal plantsAntimalarial drugsNatural drug productsSouth AfricaMalariaEthnopharmacologyAntiplasmodial screening,Bioassay-guided fractionationSesquiterpene lactonesCytotoxicityArticlePillay, P., Maharaj, V., & Smith, P. (2008). Investigating South African plants as a source of new antimalarial drugs. http://hdl.handle.net/10204/3367Pillay, P, VJ Maharaj, and PJ Smith "Investigating South African plants as a source of new antimalarial drugs." (2008) http://hdl.handle.net/10204/3367Pillay P, Maharaj V, Smith P. Investigating South African plants as a source of new antimalarial drugs. 2008; http://hdl.handle.net/10204/3367.TY - Article AU - Pillay, P AU - Maharaj, VJ AU - Smith, PJ AB - Based on the historical success of natural products as antimalarial drugs and the urgent need for new antimalarials, a number of South African medicinal plants have been evaluated for their antimalarial properties. This paper reviews the major studies conducted and their findings. Overall three ethnobotanical screening programmes have been conducted on South African plants and there have been three studies adopting a more direct approach where plants within a particular genus were screened for antiplasmodial activity. The paper also summarizes antimalarial plants, which were studied individually, as well as the bioactive molecules identified from selected active plant extracts DA - 2008-10 DB - ResearchSpace DP - CSIR KW - Medicinal plants KW - Antimalarial drugs KW - Natural drug products KW - South Africa KW - Malaria KW - Ethnopharmacology KW - Antiplasmodial screening, KW - Bioassay-guided fractionation KW - Sesquiterpene lactones KW - Cytotoxicity LK - https://researchspace.csir.co.za PY - 2008 SM - 0378-8741 T1 - Investigating South African plants as a source of new antimalarial drugs TI - Investigating South African plants as a source of new antimalarial drugs UR - http://hdl.handle.net/10204/3367 ER -