Adeleke, Oluwatoyin AKarry, KMMichniak-Kohn, BBMonama, Nkwe O2017-11-102017-11-102015-10Adeleke, O.A., Karry, K.M., Michniak-Kohn, B.B. and Monama, N.O. 2015. Computer-aided construction and investigation of a thermodynamically stable mouth-dissolving film containing isoniazid. In: American Association of Pharmaceutical Scientists Annual Meeting and Exposition, Orlando, United States of America, October 25-29, 2015http://hdl.handle.net/10204/9750American Association of Pharmaceutical Scientists Annual Meeting and Exposition, Orlando, United States of America, October 25-29, 2015The purpose of this abstract is to design and characterize a thermodynamically stable mouth-dissolving film containing isoniazid employing in silico and in vitro techniques. Isoniazid (solubility = 140 mg/mL and log P = -0.64 at 25°C) is a first-line antibiotic indicated for the prevention (as a single entity) and treatment (in combination with other medicines) of active tuberculosis infection.enIsoniazidPharmaceuticalsComputer-aided construction and investigation of a thermodynamically stable mouth-dissolving film containing isoniazidConference PresentationAdeleke, O. A., Karry, K., Michniak-Kohn, B., & Monama, N. O. (2015). Computer-aided construction and investigation of a thermodynamically stable mouth-dissolving film containing isoniazid. http://hdl.handle.net/10204/9750Adeleke, Oluwatoyin A, KM Karry, BB Michniak-Kohn, and Nkwe O Monama. "Computer-aided construction and investigation of a thermodynamically stable mouth-dissolving film containing isoniazid." (2015): http://hdl.handle.net/10204/9750Adeleke OA, Karry K, Michniak-Kohn B, Monama NO, Computer-aided construction and investigation of a thermodynamically stable mouth-dissolving film containing isoniazid; 2015. http://hdl.handle.net/10204/9750 .TY - Conference Presentation AU - Adeleke, Oluwatoyin A AU - Karry, KM AU - Michniak-Kohn, BB AU - Monama, Nkwe O AB - The purpose of this abstract is to design and characterize a thermodynamically stable mouth-dissolving film containing isoniazid employing in silico and in vitro techniques. Isoniazid (solubility = 140 mg/mL and log P = -0.64 at 25°C) is a first-line antibiotic indicated for the prevention (as a single entity) and treatment (in combination with other medicines) of active tuberculosis infection. DA - 2015-10 DB - ResearchSpace DP - CSIR KW - Isoniazid KW - Pharmaceuticals LK - https://researchspace.csir.co.za PY - 2015 T1 - Computer-aided construction and investigation of a thermodynamically stable mouth-dissolving film containing isoniazid TI - Computer-aided construction and investigation of a thermodynamically stable mouth-dissolving film containing isoniazid UR - http://hdl.handle.net/10204/9750 ER -