Jacobs, V2015-10-052015-10-052015-06Chambers, J.W. 2015. Enhanced cell mitochondrial activity using electrospun nanofibers. JSM Biochemistry and Molecular Biology, vol. 3(1), pp 1-22333-7109http://hdl.handle.net/10204/8151Copyright: 2015 JSciMed CentralResearch in tissue engineering related to the improved processes using nanofiber scaffolds has seen considerable progress in the last decade in the regeneration and construction of a number of artificial tissue types. These designs are generally viewed from the perspective of possible sources for clinical implant and transplant materials. Nowadays, advancement in engineering of tissues often referred to as threedimensional (3D) cell culture provides enhanced activities owing to the 3D systems that readily imitate the in vivo setting for differentiated organs, than a typical 2D cell culture. Electro-spinning has been useful in producing nanofibrous scaffolds with large surface area and high pore volume that has the potential to mimic the morphology of a tissue extracellular matrix and hence promoting cell attachment, proliferation and differentiation. This review reports improved processes of tissue revitalization utilizing electrospunnanofibrous scaffolds. Different tissue engineering approaches including their advantages have been discussed. Also, various biomaterials from both synthetic and natural origin have been elaborated.enCell activityElectrospinningBiomaterialsTissue engineeringArticleJacobs, V. (2015). Enhanced cell mitochondrial activity using electrospun nanofibers. http://hdl.handle.net/10204/8151Jacobs, V "Enhanced cell mitochondrial activity using electrospun nanofibers." (2015) http://hdl.handle.net/10204/8151Jacobs V. Enhanced cell mitochondrial activity using electrospun nanofibers. 2015; http://hdl.handle.net/10204/8151.TY - Article AU - Jacobs, V AB - Research in tissue engineering related to the improved processes using nanofiber scaffolds has seen considerable progress in the last decade in the regeneration and construction of a number of artificial tissue types. These designs are generally viewed from the perspective of possible sources for clinical implant and transplant materials. Nowadays, advancement in engineering of tissues often referred to as threedimensional (3D) cell culture provides enhanced activities owing to the 3D systems that readily imitate the in vivo setting for differentiated organs, than a typical 2D cell culture. Electro-spinning has been useful in producing nanofibrous scaffolds with large surface area and high pore volume that has the potential to mimic the morphology of a tissue extracellular matrix and hence promoting cell attachment, proliferation and differentiation. This review reports improved processes of tissue revitalization utilizing electrospunnanofibrous scaffolds. Different tissue engineering approaches including their advantages have been discussed. Also, various biomaterials from both synthetic and natural origin have been elaborated. DA - 2015-06 DB - ResearchSpace DP - CSIR KW - Cell activity KW - Electrospinning KW - Biomaterials KW - Tissue engineering LK - https://researchspace.csir.co.za PY - 2015 SM - 2333-7109 T1 - Enhanced cell mitochondrial activity using electrospun nanofibers TI - Enhanced cell mitochondrial activity using electrospun nanofibers UR - http://hdl.handle.net/10204/8151 ER -