Grobler, Lichelle RSuleman, EssaThimiri Govindaraj, Deepak B2021-12-032021-12-032021-02Grobler, L.R., Suleman, E. & Thimiri Govindaraj, D.B. 2021. Patents and technology transfer in CRISPR technology. <i>Progress in Molecular Biology and Translational Science, 180.</i> http://hdl.handle.net/10204/121841877-1173DOI: 10.1016/bs.pmbts.2021.01.009http://hdl.handle.net/10204/12184CRISPR technology has revolutionized biological research in the last decade and many academic institutions and companies have patented CRISPR systems and applications. Several patents have been filed for various applications of CRISPR in different industries such as agriculture, synthetic biology, bio-nanotechnology and precision medicine. Despite tremendous pressure on the technology transfer teams, several startups and spin-out companies are already using CRISPR technologies for commercial applications. In this chapter, we discuss the different CRISPR nucleases and their applications. Secondly, we detail our current opinion and perspective on the CRISPR patent and technology landscape for non-mammalian systems. We present two case-studies on CRISPR diagnostics companies, SHERLOCK and Mammoth Biosciences, who are currently at the forefront of establishing diagnostics platforms for coronavirus (SARS-CoV-2) detection. Finally, our chapter identifies future advancements and possible challenges that CRISPR technology might face in non-mammalian systems.AbstractenCRISPR technologyCRISPR patent landscapeMammoth biosciencesNon-mammalian systemPatents and technology transfer in CRISPR technologyArticleGrobler, L. R., Suleman, E., & Thimiri Govindaraj, D. B. (2021). Patents and technology transfer in CRISPR technology. <i>Progress in Molecular Biology and Translational Science, 180</i>, http://hdl.handle.net/10204/12184Grobler, Lichelle R, Essa Suleman, and Deepak B Thimiri Govindaraj "Patents and technology transfer in CRISPR technology." <i>Progress in Molecular Biology and Translational Science, 180</i> (2021) http://hdl.handle.net/10204/12184Grobler LR, Suleman E, Thimiri Govindaraj DB. Patents and technology transfer in CRISPR technology. Progress in Molecular Biology and Translational Science, 180. 2021; http://hdl.handle.net/10204/12184.TY - Article AU - Grobler, Lichelle R AU - Suleman, Essa AU - Thimiri Govindaraj, Deepak B AB - CRISPR technology has revolutionized biological research in the last decade and many academic institutions and companies have patented CRISPR systems and applications. Several patents have been filed for various applications of CRISPR in different industries such as agriculture, synthetic biology, bio-nanotechnology and precision medicine. Despite tremendous pressure on the technology transfer teams, several startups and spin-out companies are already using CRISPR technologies for commercial applications. In this chapter, we discuss the different CRISPR nucleases and their applications. Secondly, we detail our current opinion and perspective on the CRISPR patent and technology landscape for non-mammalian systems. We present two case-studies on CRISPR diagnostics companies, SHERLOCK and Mammoth Biosciences, who are currently at the forefront of establishing diagnostics platforms for coronavirus (SARS-CoV-2) detection. Finally, our chapter identifies future advancements and possible challenges that CRISPR technology might face in non-mammalian systems. DA - 2021-02 DB - ResearchSpace DP - CSIR J1 - Progress in Molecular Biology and Translational Science, 180 KW - CRISPR technology KW - CRISPR patent landscape KW - Mammoth biosciences KW - Non-mammalian system LK - https://researchspace.csir.co.za PY - 2021 SM - 1877-1173 T1 - Patents and technology transfer in CRISPR technology TI - Patents and technology transfer in CRISPR technology UR - http://hdl.handle.net/10204/12184 ER -25002