Millroy, LLondon, GVeale, RWeinberg, MKhati, M2011-09-222011-09-222011-02Millroy, L, London, G, Veale, R et al. 2011. Binding kinetics of aptamers to gp120 derived from HIV-1 subtype C. EMBO global exchange lecture course on HIV AIDS, Stellenbsoch, 30 January - 04 February 2011http://hdl.handle.net/10204/5155EMBO global exchange lecture course on HIV AIDS, Stellenbsoch, 30 January - 04 February 2011Aptamers are artificial nucleic acid ligands that can be engineered to bind with high specificity to a macromolecule. Their binding specificity and small size allow for a range of therapeutic applications. One avenue of research is to develop aptamers with specific and strong affinity to the HIV-1 envelope glycoprotein gp120 and act as novel HIV-1 entry inhibitor drugs or as targeted drug delivery systems to HIV-1 infected cells. Prior to any downstream applications, novel gp120 aptamers need to be biophysically characterised with regards to their target binding characteristics.enKineticsBinding kineticsAptamersHIV AIDSHIV-1Conference PresentationMillroy, L., London, G., Veale, R., Weinberg, M., & Khati, M. (2011). Binding kinetics of aptamers to gp120 derived from HIV-1 subtype C. Conference Poster. http://hdl.handle.net/10204/5155Millroy, L, G London, R Veale, M Weinberg, and M Khati. "Binding kinetics of aptamers to gp120 derived from HIV-1 subtype C." (2011): http://hdl.handle.net/10204/5155Millroy L, London G, Veale R, Weinberg M, Khati M, Binding kinetics of aptamers to gp120 derived from HIV-1 subtype C; Conference Poster; 2011. http://hdl.handle.net/10204/5155 .TY - Conference Presentation AU - Millroy, L AU - London, G AU - Veale, R AU - Weinberg, M AU - Khati, M AB - Aptamers are artificial nucleic acid ligands that can be engineered to bind with high specificity to a macromolecule. Their binding specificity and small size allow for a range of therapeutic applications. One avenue of research is to develop aptamers with specific and strong affinity to the HIV-1 envelope glycoprotein gp120 and act as novel HIV-1 entry inhibitor drugs or as targeted drug delivery systems to HIV-1 infected cells. Prior to any downstream applications, novel gp120 aptamers need to be biophysically characterised with regards to their target binding characteristics. DA - 2011-02 DB - ResearchSpace DP - CSIR KW - Kinetics KW - Binding kinetics KW - Aptamers KW - HIV AIDS KW - HIV-1 LK - https://researchspace.csir.co.za PY - 2011 T1 - Binding kinetics of aptamers to gp120 derived from HIV-1 subtype C TI - Binding kinetics of aptamers to gp120 derived from HIV-1 subtype C UR - http://hdl.handle.net/10204/5155 ER -