Barnard, AKotzé-Jacobs, LMoolman, S2012-04-242012-04-242011-05Barnard, A, Kotzé-Jacobs, L and Moolman, S. Optimisation of ported yield of hemispherical ported microparticles for soft tissue augmentation. International Conference on the Frontiers of Polymers and Advanced Materials (ICFPAM), Pretoria, South Africa, 22-27 May 2011978-1-86854-946-7http://hdl.handle.net/10204/5824International Conference on the Frontiers of Polymers and Advanced Materials (ICFPAM), Pretoria, South Africa, 22-27 May 2011The use of biodegradable polymers in temporary surgical and pharmacological applications has become a prominent part of polymer research. Poly(e-caprolactone) (PCL) is widely studied for tissue engineering applications due to its relatively suitable degradation period and biocompatibility. Micro-porous particles are useful in soft-tissue bulking due to their relatively large surface area, low density and high degree of porosity. In this study, the authors have developed ported porous PCL particles for soft-tissue bulking, using an oil-in-water emulsion with an internal bicarbonate phase which evolves carbon dioxide gas on reaction with a cetic acid thereby producing ports in the structure.enPolymersSoft tissue augmentationHemispherical ported microparticlesBiodegradable polymersPolymersConference PresentationBarnard, A., Kotzé-Jacobs, L., & Moolman, S. (2011). Optimisation of ported yield of hemispherical ported microparticles for soft tissue augmentation. Institute of Applied Materials, University of Pretoria. http://hdl.handle.net/10204/5824Barnard, A, L Kotzé-Jacobs, and S Moolman. "Optimisation of ported yield of hemispherical ported microparticles for soft tissue augmentation." (2011): http://hdl.handle.net/10204/5824Barnard A, Kotzé-Jacobs L, Moolman S, Optimisation of ported yield of hemispherical ported microparticles for soft tissue augmentation; Institute of Applied Materials, University of Pretoria; 2011. http://hdl.handle.net/10204/5824 .TY - Conference Presentation AU - Barnard, A AU - Kotzé-Jacobs, L AU - Moolman, S AB - The use of biodegradable polymers in temporary surgical and pharmacological applications has become a prominent part of polymer research. Poly(e-caprolactone) (PCL) is widely studied for tissue engineering applications due to its relatively suitable degradation period and biocompatibility. Micro-porous particles are useful in soft-tissue bulking due to their relatively large surface area, low density and high degree of porosity. In this study, the authors have developed ported porous PCL particles for soft-tissue bulking, using an oil-in-water emulsion with an internal bicarbonate phase which evolves carbon dioxide gas on reaction with a cetic acid thereby producing ports in the structure. DA - 2011-05 DB - ResearchSpace DP - CSIR KW - Polymers KW - Soft tissue augmentation KW - Hemispherical ported microparticles KW - Biodegradable polymers KW - Polymers LK - https://researchspace.csir.co.za PY - 2011 SM - 978-1-86854-946-7 T1 - Optimisation of ported yield of hemispherical ported microparticles for soft tissue augmentation TI - Optimisation of ported yield of hemispherical ported microparticles for soft tissue augmentation UR - http://hdl.handle.net/10204/5824 ER -