Mkhabela, VJRay, Suprakas S2014-09-162014-09-162014Mkhabela, V.J and Ray, S.S. 2014. Poly( E-caprolactone) nanocomposite scaffolds for tissue engineering: a brief overview. Journal of Nanoscience and Nanotechnology, vol. 14(1), pp 535- 5451533-4880http://hdl.handle.net/10204/7674Copyright: 2014 American Scientific Publishers. This is an ABSTRACT ONLY. The definitive version is published in Journal of Nanoscience and Nanotechnology, vol. 14(1), pp 535- 545Polycaprolactone is a bioresorbable polymer that has been extensively used in the biomaterials field and a number of drug-delivery systems. The superior rheological and viscoelastic properties of this polymer render it easy to manufacture and manipulate into a large range of medical devices and implants. The advantage of polycaprolactone over its aliphatic counterparts is that it has a long-term degradation period, which provides a good platform for the design and fabrication of implants that require long-term degradation kinetics for example in bone tissue engineering. The incorporation of nanofillers or blending of polycaprolactone with other polymers has yielded a class of hybrid materials with significantly improved physical and chemical properties such as strength, porosity, microstructure, controllable degradation rates, and bioactivity that are important for tissue engineering. This overview highlights the interesting advancements in polycaprolactone polymeric systems that relate to biological and tissue engineering applications, including aspects of technology in fabricating the scaffolds.enPolycaprolactoneNanocompositesScaffoldsTissue engineeringArticleMkhabela, V., & Ray, S. S. (2014). Poly( E-caprolactone) nanocomposite scaffolds for tissue engineering: a brief overview. http://hdl.handle.net/10204/7674Mkhabela, VJ, and Suprakas S Ray "Poly( E-caprolactone) nanocomposite scaffolds for tissue engineering: a brief overview." (2014) http://hdl.handle.net/10204/7674Mkhabela V, Ray SS. Poly( E-caprolactone) nanocomposite scaffolds for tissue engineering: a brief overview. 2014; http://hdl.handle.net/10204/7674.TY - Article AU - Mkhabela, VJ AU - Ray, Suprakas S AB - Polycaprolactone is a bioresorbable polymer that has been extensively used in the biomaterials field and a number of drug-delivery systems. The superior rheological and viscoelastic properties of this polymer render it easy to manufacture and manipulate into a large range of medical devices and implants. The advantage of polycaprolactone over its aliphatic counterparts is that it has a long-term degradation period, which provides a good platform for the design and fabrication of implants that require long-term degradation kinetics for example in bone tissue engineering. The incorporation of nanofillers or blending of polycaprolactone with other polymers has yielded a class of hybrid materials with significantly improved physical and chemical properties such as strength, porosity, microstructure, controllable degradation rates, and bioactivity that are important for tissue engineering. This overview highlights the interesting advancements in polycaprolactone polymeric systems that relate to biological and tissue engineering applications, including aspects of technology in fabricating the scaffolds. DA - 2014 DB - ResearchSpace DP - CSIR KW - Polycaprolactone KW - Nanocomposites KW - Scaffolds KW - Tissue engineering LK - https://researchspace.csir.co.za PY - 2014 SM - 1533-4880 T1 - Poly( E-caprolactone) nanocomposite scaffolds for tissue engineering: a brief overview TI - Poly( E-caprolactone) nanocomposite scaffolds for tissue engineering: a brief overview UR - http://hdl.handle.net/10204/7674 ER -