Walters, Chavon RPool, ESomerset, V2017-07-282017-07-282016-10Walters, C.R., Pool, E. and Somerset, V. 2016. Nanotoxicology: A review. In: Toxicology - New Aspects to This Scientific Conundrum: 45-63. DOI: 10.5772/62600978-953-51-2717-8DOI: 10.5772/62600https://www.intechopen.com/books/toxicology-new-aspects-to-this-scientific-conundrumhttp://hdl.handle.net/10204/9436© 2016 The Author(s). Licensee InTech. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Nanotoxicology represents a new and growing research area in toxicology. It deals with the assessment of the toxicological properties of nanoparticles (NPs) with the intention of determining whether (and to what extent) they pose an environmental or societal threat. Inherent properties of NPs (including size, shape, surface area, surface charge, crystal structure, coating, and solubility/dissolution) as well as environmental factors (such as temperature, pH, ionic strength, salinity, and organic matter) collectively influence NP behavior, fate and transport, and ultimately toxicity. The mechanisms underlying the toxicity of nanomaterials (NMs) have recently been studied extensively. Reactive oxygen species (ROS) toxicity represents one such mechanism. An overproduction of ROS induces oxidative stress, resulting in inability of the cells to maintain normal physiological redoxregulated functions. In the context of this book, this chapter includes topics pertaining to chemical and physical properties of NMs and characterization for proper toxicological evaluation, exposure, and environmental fate and transport, and ecological and genotoxic effects. This chapter reviews the available research pertaining specifically to NMs in the aquatic environment (in plants, aquatic invertebrates, and fish) and their use in biomarker studies.enNanomaterialsCharacterization techniquesNanotoxicologyBiomarkersAnalytical methodsIn vitro studiesIn vivo studiesBook ChapterWalters, C. R., Pool, E., & Somerset, V. (2016). Nanotoxicology: A review., <i>Worklist;19012</i> INTECH. http://hdl.handle.net/10204/9436Walters, Chavon R, E Pool, and V Somerset. "Nanotoxicology: A review" In <i>WORKLIST;19012</i>, n.p.: INTECH. 2016. http://hdl.handle.net/10204/9436.Walters CR, Pool E, Somerset V. Nanotoxicology: A review.. Worklist;19012. [place unknown]: INTECH; 2016. [cited yyyy month dd]. http://hdl.handle.net/10204/9436.TY - Book Chapter AU - Walters, Chavon R AU - Pool, E AU - Somerset, V AB - Nanotoxicology represents a new and growing research area in toxicology. It deals with the assessment of the toxicological properties of nanoparticles (NPs) with the intention of determining whether (and to what extent) they pose an environmental or societal threat. Inherent properties of NPs (including size, shape, surface area, surface charge, crystal structure, coating, and solubility/dissolution) as well as environmental factors (such as temperature, pH, ionic strength, salinity, and organic matter) collectively influence NP behavior, fate and transport, and ultimately toxicity. The mechanisms underlying the toxicity of nanomaterials (NMs) have recently been studied extensively. Reactive oxygen species (ROS) toxicity represents one such mechanism. An overproduction of ROS induces oxidative stress, resulting in inability of the cells to maintain normal physiological redoxregulated functions. In the context of this book, this chapter includes topics pertaining to chemical and physical properties of NMs and characterization for proper toxicological evaluation, exposure, and environmental fate and transport, and ecological and genotoxic effects. This chapter reviews the available research pertaining specifically to NMs in the aquatic environment (in plants, aquatic invertebrates, and fish) and their use in biomarker studies. DA - 2016-10 DB - ResearchSpace DP - CSIR KW - Nanomaterials KW - Characterization techniques KW - Nanotoxicology KW - Biomarkers KW - Analytical methods KW - In vitro studies KW - In vivo studies LK - https://researchspace.csir.co.za PY - 2016 SM - 978-953-51-2717-8 T1 - Nanotoxicology: A review TI - Nanotoxicology: A review UR - http://hdl.handle.net/10204/9436 ER -