Sadiku, ERFasiku, VOOwonubi, SJMukwevho, EAderibigbe, BALemmer, YolandyAbbavaram, BRManjula, BNkuna, CDludlu, MK2019-02-222019-02-222018-05Sadiku, E.R., Fasiku, V.O., Owonubi, S.J., et al… 2018. Polyhydroxyalkanoates (PHAs) as scaffolds for tissue engineering. Polyhydroxyalkanoates, Biosynthesis, Chemical Structures and Applications. Nova Science Publishers: New York978-1-53613-439-1http://www.ipben.unesp.br/Home/livros/polyhydroxyalkanoates-ebook-de-paula-et-al.-chapter.pdf#page=223http://hdl.handle.net/10204/10718Copyright: Nova Science Publishers: New York. Due to copyright restrictions, the attached PDF file only contains the abstract of the full text item.Tissue engineering is a filed that has gained a lot of advancement since the discovery of biopolymers. Biopolymers are polymers produced by living organisms: that is, they are polymeric biomolecules. They consist of monomeric units that ar covalently bonded to one another in order to form larger structures. Biopolymers have been widely used as biomaterials for the construction of tissue engineering scaffold. Scaffolds have been used for tissue engineering, such as: bone, cartilage, ligament, skin, vascular tissues, neural tissues, and skeletal muscles. Polyhydroxyester is a typical example of biopolymers that have been employed for this application. Their exceptional properties such as high surface-to-volume ratio, high porosity with vwery small pore size, biodegradation, and mechanical property have made them gain a lot of attention in this field. Also, they have advantages which are significant for tissue engineering. This chapter will focus on the production, modification, properties and medical applications of polyhydroxyesters, such as PLA (Polylactide), PGA (Polyglycolide or poly(glycolic acid), PCL (Polycaprolactone), poly(ester amide)s and PLGA (Poly(lactide-co-glycolide), with particular emphasis on the different plyhydroxyalkanoates (PHAs), which have divrse applicatioins in tissue engineering.enBiopolymerScaffoldsPolyhydroxyestersPHAsPolyhydroxyalkanoatesTissue engineeringBook ChapterSadiku, E., Fasiku, V., Owonubi, S., Mukwevho, E., Aderibigbe, B., Lemmer, Y., ... Dludlu, M. (2018). Polyhydroxyalkanoates (PHAs) as scaffolds for tissue engineering., <i>Workflow;21395</i> New York: Nova Science Publishers. http://hdl.handle.net/10204/10718Sadiku, ER, VO Fasiku, SJ Owonubi, E Mukwevho, BA Aderibigbe, Yolandy Lemmer, BR Abbavaram, B Manjula, C Nkuna, and MK Dludlu. "Polyhydroxyalkanoates (PHAs) as scaffolds for tissue engineering" In <i>WORKFLOW;21395</i>, n.p.: New York: Nova Science Publishers. 2018. http://hdl.handle.net/10204/10718.Sadiku E, Fasiku V, Owonubi S, Mukwevho E, Aderibigbe B, Lemmer Y, et al. Polyhydroxyalkanoates (PHAs) as scaffolds for tissue engineering.. Workflow;21395. [place unknown]: New York: Nova Science Publishers; 2018. [cited yyyy month dd]. http://hdl.handle.net/10204/10718.TY - Book Chapter AU - Sadiku, ER AU - Fasiku, VO AU - Owonubi, SJ AU - Mukwevho, E AU - Aderibigbe, BA AU - Lemmer, Yolandy AU - Abbavaram, BR AU - Manjula, B AU - Nkuna, C AU - Dludlu, MK AB - Tissue engineering is a filed that has gained a lot of advancement since the discovery of biopolymers. Biopolymers are polymers produced by living organisms: that is, they are polymeric biomolecules. They consist of monomeric units that ar covalently bonded to one another in order to form larger structures. Biopolymers have been widely used as biomaterials for the construction of tissue engineering scaffold. Scaffolds have been used for tissue engineering, such as: bone, cartilage, ligament, skin, vascular tissues, neural tissues, and skeletal muscles. Polyhydroxyester is a typical example of biopolymers that have been employed for this application. Their exceptional properties such as high surface-to-volume ratio, high porosity with vwery small pore size, biodegradation, and mechanical property have made them gain a lot of attention in this field. Also, they have advantages which are significant for tissue engineering. This chapter will focus on the production, modification, properties and medical applications of polyhydroxyesters, such as PLA (Polylactide), PGA (Polyglycolide or poly(glycolic acid), PCL (Polycaprolactone), poly(ester amide)s and PLGA (Poly(lactide-co-glycolide), with particular emphasis on the different plyhydroxyalkanoates (PHAs), which have divrse applicatioins in tissue engineering. DA - 2018-05 DB - ResearchSpace DP - CSIR KW - Biopolymer KW - Scaffolds KW - Polyhydroxyesters KW - PHAs KW - Polyhydroxyalkanoates KW - Tissue engineering LK - https://researchspace.csir.co.za PY - 2018 SM - 978-1-53613-439-1 T1 - Polyhydroxyalkanoates (PHAs) as scaffolds for tissue engineering TI - Polyhydroxyalkanoates (PHAs) as scaffolds for tissue engineering UR - http://hdl.handle.net/10204/10718 ER -