Lotter, JBotes, ALVan Dyk, MSBreytenbach, JC2007-02-062007-06-072007-02-062007-06-072004-08Lotter, J, et al. 2004. Correlation between the physicochemical properties of organic solvents and their biocompatibility toward epoxide hydrolase activity in whole-cells of a yeast, Rhodotorulasp. Biotechnology Letters, vol 26 (15), pp 1191-11950141-5492http://hdl.handle.net/10204/1514http://hdl.handle.net/10204/1514Epoxides are often highly hydrophobic substrates and the presence of an organic co-solvent within an aqueous bioreactor is in such cases indicated. The effect of 40 water-miscible and -immiscible organic solvents on epoxide hydrolase activity in whole-cells of the yeast Rhodotorula sp. UOFS Y-0448 was investigated. No formal correlation between solvent biocompatibility and physicochemical properties was deductible, although the introduction of hydroxyl groups increased biocompatibility. 1-Pentanol, 2-methylcyclohexanol and 1-octanol were the most biocompatible resulting in relatively low activity losses when used at up to 20% (v/v).310444 bytesapplication/pdfenCopyright: 2004 Kluwer Academic PublisherBiotransformationsCo-solventsEpoxide hydrolasesYeastsArticleLotter, J., Botes, A., Van Dyk, M., & Breytenbach, J. (2004). Correlation between the physicochemical properties of organic solvents and their biocompatibility toward epoxide hydrolase activity in whole-cells of a yeast, Rhodotorulasp. http://hdl.handle.net/10204/1514Lotter, J, AL Botes, MS Van Dyk, and JC Breytenbach "Correlation between the physicochemical properties of organic solvents and their biocompatibility toward epoxide hydrolase activity in whole-cells of a yeast, Rhodotorulasp." (2004) http://hdl.handle.net/10204/1514Lotter J, Botes A, Van Dyk M, Breytenbach J. Correlation between the physicochemical properties of organic solvents and their biocompatibility toward epoxide hydrolase activity in whole-cells of a yeast, Rhodotorulasp. 2004; http://hdl.handle.net/10204/1514.TY - Article AU - Lotter, J AU - Botes, AL AU - Van Dyk, MS AU - Breytenbach, JC AB - Epoxides are often highly hydrophobic substrates and the presence of an organic co-solvent within an aqueous bioreactor is in such cases indicated. The effect of 40 water-miscible and -immiscible organic solvents on epoxide hydrolase activity in whole-cells of the yeast Rhodotorula sp. UOFS Y-0448 was investigated. No formal correlation between solvent biocompatibility and physicochemical properties was deductible, although the introduction of hydroxyl groups increased biocompatibility. 1-Pentanol, 2-methylcyclohexanol and 1-octanol were the most biocompatible resulting in relatively low activity losses when used at up to 20% (v/v). DA - 2004-08 DB - ResearchSpace DP - CSIR KW - Biotransformations KW - Co-solvents KW - Epoxide hydrolases KW - Yeasts LK - https://researchspace.csir.co.za PY - 2004 SM - 0141-5492 T1 - Correlation between the physicochemical properties of organic solvents and their biocompatibility toward epoxide hydrolase activity in whole-cells of a yeast, Rhodotorulasp TI - Correlation between the physicochemical properties of organic solvents and their biocompatibility toward epoxide hydrolase activity in whole-cells of a yeast, Rhodotorulasp UR - http://hdl.handle.net/10204/1514 ER -