Mutorwa, MSalisu, SBlatch, GLKenyon, CKaye, PT2011-11-302011-11-302009-01Mutorwa, M, Salisu, S, Blatch, GL et al. 2009. 3-substituted anilines as scaffolds for the construction of glutamine synthetase and DXP-reductoisomerase inhibitors. Synthetic Communications, 39(15), pp 2723 - 27360039-7911http://www.tandfonline.com/doi/abs/10.1080/00397910802663444#previewhttp://hdl.handle.net/10204/5353Copyright: 2009 Taylor & Francis. This is an ABSTRACT ONLYAccess to a series of truncated ATP analogs, as potential anti-tuberculosis agents, has been explored via alkylation and acylation of 3-aminophenol, whereas chloroacetylation, using chloroacetyl chloride, and subsequent Arbuzov phosphonation of a series of 3-substituted anilines have afforded a series of phosphonate derivatives as potential antimalarial agents.enAniline derivativesDXP-reductoisomerase inhibitorsGlutamine synthetasePhosphonatesSynthetic communicationsArticleMutorwa, M., Salisu, S., Blatch, G., Kenyon, C., & Kaye, P. (2009). 3-substituted anilines as scaffolds for the construction of glutamine synthetase and DXP-reductoisomerase inhibitors. http://hdl.handle.net/10204/5353Mutorwa, M, S Salisu, GL Blatch, C Kenyon, and PT Kaye "3-substituted anilines as scaffolds for the construction of glutamine synthetase and DXP-reductoisomerase inhibitors." (2009) http://hdl.handle.net/10204/5353Mutorwa M, Salisu S, Blatch G, Kenyon C, Kaye P. 3-substituted anilines as scaffolds for the construction of glutamine synthetase and DXP-reductoisomerase inhibitors. 2009; http://hdl.handle.net/10204/5353.TY - Article AU - Mutorwa, M AU - Salisu, S AU - Blatch, GL AU - Kenyon, C AU - Kaye, PT AB - Access to a series of truncated ATP analogs, as potential anti-tuberculosis agents, has been explored via alkylation and acylation of 3-aminophenol, whereas chloroacetylation, using chloroacetyl chloride, and subsequent Arbuzov phosphonation of a series of 3-substituted anilines have afforded a series of phosphonate derivatives as potential antimalarial agents. DA - 2009-01 DB - ResearchSpace DP - CSIR KW - Aniline derivatives KW - DXP-reductoisomerase inhibitors KW - Glutamine synthetase KW - Phosphonates KW - Synthetic communications LK - https://researchspace.csir.co.za PY - 2009 SM - 0039-7911 T1 - 3-substituted anilines as scaffolds for the construction of glutamine synthetase and DXP-reductoisomerase inhibitors TI - 3-substituted anilines as scaffolds for the construction of glutamine synthetase and DXP-reductoisomerase inhibitors UR - http://hdl.handle.net/10204/5353 ER -