Mokhena, Teboho CLuyt, AS2017-09-042017-09-042017-06Mokhena, T.M. and Luyt, A.S. 2017. Electrospun alginate nanofibres impregnated with silver nanoparticles: Preparation, morphology and antibacterial properties. Carbohydrate Polymers, vol. 165(1): 304-312. http://dx.doi.org/10.1016/j.carbpol.2017.02.0680144-8617http://dx.doi.org/10.1016/j.carbpol.2017.02.068http://www.sciencedirect.com/science/article/pii/S0144861717301984http://hdl.handle.net/10204/9526Copyright: 2017 Elsevier. Due to copyright restrictions, the attached PDF file only contains the abstract of the full text item. For access to the full text item, kindly consult the publisher's website.Silver nanoparticles are amongst the most valuable nanoparticles with interesting properties, such as a non-toxic nature and high antibacterial efficiency, making them applicable for tissue scaffold, protective clothing and wound dressing. In this study, silver nanoparticles (AgNPs) have been synthesized using chitosan as reducing and stabilizing agent. The formation of silver nanoparticles was confirmed by UV-vis, and the TEM showed that different shapes were obtained depending on the heating duration. The chitosan/AgNPs was coated onto an electrospun alginate membrane to produce stable polyelectrolyte complex (PEC) nanofibre composites with high antibacterial efficiency. These composites were characterized by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD). AgNPs were successfully impregnated into the PEC nanofibre composite, while there was complexation between the electrospun alginate and the chitosan/AgNPs composite. PEC demonstrated a good antibacterial activity against both gram negative and gram positive bacteria with acceptable water vapour transmission within the range required for the treatment of injuries or wounds.enChitosanSilver nanoparticlesElectrospun alginatePolyelectrolyte complexAntibacterial activityArticleMokhena, T. C., & Luyt, A. (2017). Electrospun alginate nanofibres impregnated with silver nanoparticles: Preparation, morphology and antibacterial properties. http://hdl.handle.net/10204/9526Mokhena, Teboho C, and AS Luyt "Electrospun alginate nanofibres impregnated with silver nanoparticles: Preparation, morphology and antibacterial properties." (2017) http://hdl.handle.net/10204/9526Mokhena TC, Luyt A. Electrospun alginate nanofibres impregnated with silver nanoparticles: Preparation, morphology and antibacterial properties. 2017; http://hdl.handle.net/10204/9526.TY - Article AU - Mokhena, Teboho C AU - Luyt, AS AB - Silver nanoparticles are amongst the most valuable nanoparticles with interesting properties, such as a non-toxic nature and high antibacterial efficiency, making them applicable for tissue scaffold, protective clothing and wound dressing. In this study, silver nanoparticles (AgNPs) have been synthesized using chitosan as reducing and stabilizing agent. The formation of silver nanoparticles was confirmed by UV-vis, and the TEM showed that different shapes were obtained depending on the heating duration. The chitosan/AgNPs was coated onto an electrospun alginate membrane to produce stable polyelectrolyte complex (PEC) nanofibre composites with high antibacterial efficiency. These composites were characterized by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD). AgNPs were successfully impregnated into the PEC nanofibre composite, while there was complexation between the electrospun alginate and the chitosan/AgNPs composite. PEC demonstrated a good antibacterial activity against both gram negative and gram positive bacteria with acceptable water vapour transmission within the range required for the treatment of injuries or wounds. DA - 2017-06 DB - ResearchSpace DO - 10.1016/j.carbpol.2017.02.068 DP - CSIR KW - Chitosan KW - Silver nanoparticles KW - Electrospun alginate KW - Polyelectrolyte complex KW - Antibacterial activity LK - https://researchspace.csir.co.za PY - 2017 SM - 0144-8617 T1 - Electrospun alginate nanofibres impregnated with silver nanoparticles: Preparation, morphology and antibacterial properties TI - Electrospun alginate nanofibres impregnated with silver nanoparticles: Preparation, morphology and antibacterial properties UR - http://hdl.handle.net/10204/9526 ER -