Naidoo, KerschRolfes, HEaston, KMoolman, SChetty, ARichter, WNilen, R2009-05-112009-05-112008Naidoo, K et al. 2008. Emulsion preparation for novel micro-porous polymeric hemi-shells. Materials Letters, Vol. 62, pp 252-2540167-577Xhttp://hdl.handle.net/10204/3369Copyroght: 2007 ElsevierA modified oil-in-water (O/W) emulsion process was developed to produce novel micro-porous hemi-spherical polycaprolactone (PCL) micro-particles called "hemi-shells". By addition of a porogen such as sodium bicarbonate (NaHCO3) into the PCL-dichloromethane (DCM) oil phase and emulsification in an acidic polyvinyl alcohol (PVA) aqueous phase, micro-porous hemi-shells formed as solvent evaporated. CO2 gas evolution from the porogen created particles with an externally micro-porous shell and a large internal cavity. The hemi-shells were characterized by SEM and optical microscopy. The number-average particle yield in the 50-200 µm range was 84%. The number-average hemi-shell yield in the same size range was 41%. These novel micro-particles have potential applications in tissue engineering and drug deliveryenNovel micro-porous polymeric hemi-shellsHemi-shellsPCLPorogenArticleNaidoo, K., Rolfes, H., Easton, K., Moolman, S., Chetty, A., Richter, W., & Nilen, R. (2008). Emulsion preparation for novel micro-porous polymeric hemi-shells. http://hdl.handle.net/10204/3369Naidoo, Kersch, H Rolfes, K Easton, S Moolman, A Chetty, W Richter, and R Nilen "Emulsion preparation for novel micro-porous polymeric hemi-shells." (2008) http://hdl.handle.net/10204/3369Naidoo K, Rolfes H, Easton K, Moolman S, Chetty A, Richter W, et al. Emulsion preparation for novel micro-porous polymeric hemi-shells. 2008; http://hdl.handle.net/10204/3369.TY - Article AU - Naidoo, Kersch AU - Rolfes, H AU - Easton, K AU - Moolman, S AU - Chetty, A AU - Richter, W AU - Nilen, R AB - A modified oil-in-water (O/W) emulsion process was developed to produce novel micro-porous hemi-spherical polycaprolactone (PCL) micro-particles called "hemi-shells". By addition of a porogen such as sodium bicarbonate (NaHCO3) into the PCL-dichloromethane (DCM) oil phase and emulsification in an acidic polyvinyl alcohol (PVA) aqueous phase, micro-porous hemi-shells formed as solvent evaporated. CO2 gas evolution from the porogen created particles with an externally micro-porous shell and a large internal cavity. The hemi-shells were characterized by SEM and optical microscopy. The number-average particle yield in the 50-200 µm range was 84%. The number-average hemi-shell yield in the same size range was 41%. These novel micro-particles have potential applications in tissue engineering and drug delivery DA - 2008 DB - ResearchSpace DP - CSIR KW - Novel micro-porous polymeric hemi-shells KW - Hemi-shells KW - PCL KW - Porogen LK - https://researchspace.csir.co.za PY - 2008 SM - 0167-577X T1 - Emulsion preparation for novel micro-porous polymeric hemi-shells TI - Emulsion preparation for novel micro-porous polymeric hemi-shells UR - http://hdl.handle.net/10204/3369 ER -