Zeevaart, JGParkinson, CJDe Koning, CB2007-02-062007-06-072007-02-062007-06-072004-05-24Zeevaart, JG, Parkinson, CJ and De Koning, CB. 2004. Palladium-catalysed arylation of acetoacetate esters to yield 2-arylacetic acid esters. Tetrahedron Letters, vol. 45(22), pp 4261-42640040-4039http://hdl.handle.net/10204/1502http://hdl.handle.net/10204/1502The coupling reaction between ethyl acetoacetate and a number of aryl halides in the presence of palladium acetate, a bulky and electron rich phosphine and K3PO4 is described. The arylated acetoacetate ester is de-acylated under the reaction conditions resulting in the generation of 2-arylacetic acid esters, constituting a mild alternative to direct arylation of carboxylate esters.256012 bytesapplication/pdfenCopyright: 2004 Pergamon-Elsevier Science LtdPalladium catalysisEnolate arylationArylacetic acid estersOrganic chemistryArticleZeevaart, J., Parkinson, C., & De Koning, C. (2004). Palladium-catalysed arylation of acetoacetate esters to yield 2-arylacetic acid esters. http://hdl.handle.net/10204/1502Zeevaart, JG, CJ Parkinson, and CB De Koning "Palladium-catalysed arylation of acetoacetate esters to yield 2-arylacetic acid esters." (2004) http://hdl.handle.net/10204/1502Zeevaart J, Parkinson C, De Koning C. Palladium-catalysed arylation of acetoacetate esters to yield 2-arylacetic acid esters. 2004; http://hdl.handle.net/10204/1502.TY - Article AU - Zeevaart, JG AU - Parkinson, CJ AU - De Koning, CB AB - The coupling reaction between ethyl acetoacetate and a number of aryl halides in the presence of palladium acetate, a bulky and electron rich phosphine and K3PO4 is described. The arylated acetoacetate ester is de-acylated under the reaction conditions resulting in the generation of 2-arylacetic acid esters, constituting a mild alternative to direct arylation of carboxylate esters. DA - 2004-05-24 DB - ResearchSpace DP - CSIR KW - Palladium catalysis KW - Enolate arylation KW - Arylacetic acid esters KW - Organic chemistry LK - https://researchspace.csir.co.za PY - 2004 SM - 0040-4039 T1 - Palladium-catalysed arylation of acetoacetate esters to yield 2-arylacetic acid esters TI - Palladium-catalysed arylation of acetoacetate esters to yield 2-arylacetic acid esters UR - http://hdl.handle.net/10204/1502 ER -